Change of serum transferrin receptor due to malarial infection, an experiment in Plasmodium gallinaceum infected chicken model.

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dc.contributor.authorWiwanitkit, Virojen_US
dc.contributor.authorParitpokee, Naraen_US
dc.contributor.authorNithiuthai, Suwanneeen_US
dc.contributor.authorBoonchalermvichian, Chaiyapornen_US
dc.contributor.authorBhokaisawan, Narudeeen_US
dc.date.accessioned2007-12-21en_US
dc.date.accessioned2009-06-02T15:41:33Z
dc.date.available2007-12-21en_US
dc.date.available2009-06-02T15:41:33Z
dc.date.issued2007-12-21en_US
dc.description.abstractBACKGROUND & OBJECTIVES: The serum transferrin receptor (sTfR) concentration in an individual reflects the extent of erythropoietic activity and is considered as an useful marker of iron deficiency independent of concurrent inflammation or infection. However, data on the impact of malaria on this parameter are ambiguous. METHODS: Here we performed an animal experiment to study the chronological change of serum transferrin receptor due to infection of Plasmodium gallinaceum. In this pilot study, we performed control experimental infection of P. gallinaceum to four newborn chicken from the same batch. We collected the venous blood samples from all chicken on Day 7 and 14. All samples were analysed for sTfR level by the immunoturbidimetric assay. RESULTS: The average level of sTfR level of the control chicken was 1.24 +/- 1.58 mg/L (range 0.18 to 3.52 mg/L). The average level of sTfR level of the experimental chicken on Day 7 was 5.42 +/- 2.19 mg/L (range 3.22 to13.94 mg/L). CONCLUSION: Although the trend of increase was observed but no significance was observed (p > 0.05). The results from this pilot study can be a good basic data for the further study in this area.en_US
dc.description.affiliationDepartment of Laboratory Medicine, Faculty of Medicine Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.comen_US
dc.identifier.citationWiwanitkit V, Paritpokee N, Nithiuthai S, Boonchalermvichian C, Bhokaisawan N. Change of serum transferrin receptor due to malarial infection, an experiment in Plasmodium gallinaceum infected chicken model. Journal of Vector Borne Diseases. 2007 Dec; 44(4): 255-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/117919
dc.language.isoengen_US
dc.source.urihttps://www.mrcindia.org/journal/en_US
dc.subject.meshAnimalsen_US
dc.subject.meshChickensen_US
dc.subject.meshMalaria, Avian --blooden_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshPlasmodium gallinaceumen_US
dc.subject.meshReceptors, Transferrin --blooden_US
dc.subject.meshTime Factorsen_US
dc.titleChange of serum transferrin receptor due to malarial infection, an experiment in Plasmodium gallinaceum infected chicken model.en_US
dc.typeJournal Articleen_US
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