In vitro responsiveness of hamster corpora lutea undergoing luteolysis to luteinizing hormone.
| dc.contributor.author | Mukku, Venkat Ramaiah | |
| dc.contributor.author | Moudgal, N R | |
| dc.date.accessioned | 2015-07-18T11:07:26Z | |
| dc.date.available | 2015-07-18T11:07:26Z | |
| dc.date.issued | 1979-12 | |
| dc.description.abstract | Corpora lutea removed from pregnant hamster deprived of endogenous luteinizing hormone for varying periods were compared for their responsiveness to externally added luteinizing hormone. The corpora lutea removed on the 8th day of pregnancy exhibited a dose-dependent increase in progesterone production in response to added luteinizing hormone upto a concentration of 2·5 μg/ml. The total progesterone synthesised by the corpora lutea decreased with increase in the duration of in vivo luteinizing hormone deprivation. However, the hormone deprivation had to be for a minimum period of 24 h before a marked reduction in the in vitro responsiveness could be seen. Neutralisation of endogenous luteinizing hormone increased the luteal cholesterol ester concentration, while in vitro incubation of such tissue with luteinizing hormone resulted in a marked reduction in cholesterol ester levels. Corpora lutea removed from hamsters on day 8, 15 and 16 of pregnancy when compared for their responsiveness in vitro to added luteinizing hormone showed that the luteal tissue of day 8 produced more progesterone relative to those of day 15/16. In contrast, depletion of free and esterified cholesterol increased with the increase in age of corpora lutea (from 15% on day 8 to 67% on day 16). | en_US |
| dc.identifier.citation | Mukku Venkat Ramaiah, Moudgal N R. In vitro responsiveness of hamster corpora lutea undergoing luteolysis to luteinizing hormone. Journal of Biosciences. 1979 Dec; 1(4): 457-465. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/160054 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ias.ac.in/jarch/jbiosci/1/457-465.pdf | en_US |
| dc.subject | Luteolysis | en_US |
| dc.subject | luteinizing hormone | en_US |
| dc.subject | progesterone | en_US |
| dc.subject | hamster | en_US |
| dc.title | In vitro responsiveness of hamster corpora lutea undergoing luteolysis to luteinizing hormone. | en_US |
| dc.type | Article | en_US |