Cancer cachexia: pathophysiologic aspects and treatment options.

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dc.contributor.authorTopkan, Erkanen_US
dc.contributor.authorYavuz, Ali Aydinen_US
dc.contributor.authorOzyilkan, Ozguren_US
dc.date.accessioned2009-05-27T17:52:06Z
dc.date.available2009-05-27T17:52:06Z
dc.date.issued2007-07-28en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention. 47 references.en_US
dc.description.abstractCancer cachexia is a syndrome characterized with progressive weight loss and abnormal wasting of fat and muscle tissue, and affects 40 to 85% of all terminally ill patients, accounting more than 20% of all cancer deaths. Current treatment for cancer cachexia principally depends on its prevention rather than reversing the present disease state, and the clinical results are far from being satisfactory. Although the exact mechanism and predisposing factors have yet to be clarified in detail, our growing knowledge about the pathophysiology and biochemical changes considering this life threatening condition should help in development of future therapeutic strategies. In the present paper, the current preclinical and clinical features considering the pathophysiology and treatment of cancer related cachexia are reviewed.en_US
dc.description.affiliationDepartment of Radiation Oncology, Baskent University Medical Faculty, Adana Research and Treatment Centre, 01120, Adana/ Turkey. drerkantopkan@yahoo.comen_US
dc.identifier.citationTopkan E, Yavuz AA, Ozyilkan O. Cancer cachexia: pathophysiologic aspects and treatment options. Asian Pacific Journal of Cancer Prevention. 2007 Jul-Sep; 8(3): 445-51en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/38054
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshAppetite Stimulants --therapeutic useen_US
dc.subject.meshCachexia --etiologyen_US
dc.subject.meshDietary Supplementsen_US
dc.subject.meshHumansen_US
dc.subject.meshNeoplasms --complicationsen_US
dc.titleCancer cachexia: pathophysiologic aspects and treatment options.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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