Comparison of Effect of Enalapril and Losartan Monotherapy on Quality of Life and Safety of Stage 1 Hypertensive Patients.
dc.contributor.author | Maharshi, Vikas | |
dc.contributor.author | Rehan, Harmeet Singh | |
dc.contributor.author | Gupta, Lalit Kumar | |
dc.contributor.author | Yadav, Madhur | |
dc.date.accessioned | 2016-12-08T07:30:04Z | |
dc.date.available | 2016-12-08T07:30:04Z | |
dc.date.issued | 2016-04 | |
dc.description.abstract | An open label randomized controlled study was conducted to compare the quality of life (QoL) and safety of newly diagnosed stage 1 hypertensive patients randomized into two groups of 30 receiving either enalapril 5 mg or losartan 50 mg per-oral once daily for three months. QoL was assessed at the baseline and at the end of study using SF-36v2 health care questionnaire. Adverse drug reactions (ADRs) were monitored. Investigations at baseline were compared with those after intervention. Pre & post-intervention QoL transformed scores within each group and change in the same between two groups were analyzed using paired and unpaired t-test respectively. Transformed scores of role limitation due to energy/fatigue, emotional well being and general health domains improved significantly in both treatment groups. Scores of bodily pain improved significantly (p=0.0008) in losartan group only. Results were not significantly different between two groups (except for bodily pain). No serious ADR was reported. | en_US |
dc.identifier.citation | Vikas Maharshi*, Harmeet Singh Rehan, Lalit Kumar Gupta and Madhur Yadav. Comparison of Effect of Enalapril and Losartan Monotherapy on Quality of Life and Safety of Stage 1 Hypertensive Patients. Indian Journal of Physiology and Pharmacology. 2016 Apr-Jun; 60(2): 174-181. | en_US |
dc.identifier.issn | 0019-5499 | |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/179556 | |
dc.language.iso | en | en_US |
dc.source.uri | https://www.ijpp.com/IJPP%20archives/2016_60_2/174-181.pdf | en_US |
dc.title | Comparison of Effect of Enalapril and Losartan Monotherapy on Quality of Life and Safety of Stage 1 Hypertensive Patients. | en_US |
dc.type | Article | en_US |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- ijpp2016v60n2p174.pdf
- Size:
- 53.07 KB
- Format:
- Adobe Portable Document Format
- Description:
- Original article
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: