Prevalence of Thyroid Dysfunction in Down’s Syndrome

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dc.contributor.authorAmbike, Mandaren_US
dc.contributor.authorChopade, Dnyandeoen_US
dc.date.accessioned2020-09-24T07:53:13Z
dc.date.available2020-09-24T07:53:13Z
dc.date.issued2020-07
dc.description.abstractIntroduction: Association of Down’s syndrome and Hypothyroidism is reported since long time. It is difficult to diagnose Hypothyroidism in Down’s syndrome as the symptoms overlap. Different studies reveal different views regarding the association. So in present study we tried to find out the association between Down’ syndrome and Hypothyroidism. Methodology: Present study was conducted at “Down Syndrome care association, Nashik, India”. The study group was 68 known cases of Down’s syndrome. TSH levels were obtained from blood sample at the earliest. Data was analysed statistically. Results: Overall population had 36% cases had high TSH levels. High TSH level in children below 5 years is 24%. The high level of TSH in children of the age group 5 years to 10 years is 46%. And percentage of children above the age of 10 years with high TSH level is 83.34%. Conclusion: Percentage of thyroid dysfunction is defiantly higher in children’s suffering from Down’ syndrome than normal population. Percentage goes higher as the age increases, so periodic check-up of thyroid function is recommended.en_US
dc.identifier.affiliationsSymbiosis International (Deemed) University, Symbiosis Medical College for Woman, Lavale, Pune, Indiaen_US
dc.identifier.affiliationsGenetic Health and Research Centre, Nashik, Indiaen_US
dc.identifier.citationAmbike Mandar, Chopade Dnyandeo. Prevalence of Thyroid Dysfunction in Down’s Syndrome. International Journal of Medical Research & Health Sciences. 2020 Jul; 9(7): 32-38en_US
dc.identifier.issn2319-5886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/205227
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber7en_US
dc.relation.volume9en_US
dc.source.urihttps://www.ijmrhs.com/abstract/prevalence-of-thyroid-dysfunction-in-downs-syndrome-47263.htmlen_US
dc.subjectDown’s Syndromeen_US
dc.subjectThyroid dysfunctionen_US
dc.subjectThyroid stimulating hormoneen_US
dc.titlePrevalence of Thyroid Dysfunction in Down’s Syndromeen_US
dc.typeJournal Articleen_US
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