Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds.

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dc.contributor.authorKarthic, Ken_US
dc.contributor.authorKirthiram, K Sen_US
dc.contributor.authorSadasivam, Sen_US
dc.contributor.authorThayumanavan, Ben_US
dc.date.accessioned2009-05-28T12:23:51Z
dc.date.available2009-05-28T12:23:51Z
dc.date.issued2008-09-28en_US
dc.description.abstractThe aqueous extract of S. cumini or Eugenia jambolana seeds and Psidium guajava leaves showed higher inhibition against the porcine pancreatic alpha-amylase among the medicinal plants studied. The alpha-amylase inhibitors from S. cumini seeds were separated from the extract by preparative thin layer chromatography into fractions with different Rf values. The fraction with Rf value between 0.285 and 0.43, which showed maximum inhibitory activity, was eluted and analyzed through LC-MS. The compounds identified from the seed extract ofS. cumini were betulinic acid and 3,5,7,4'-tetrahydroxy flavanone, which were reported earlier from S. formosanum and other plants. Dixon plot showed that the inhibition was noncompetitive in nature.en_US
dc.description.affiliationDepartment of Biotechnology, Kumaraguru College of Technology, Coimbatore 641 006, India.en_US
dc.identifier.citationKarthic K, Kirthiram KS, Sadasivam S, Thayumanavan B. Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds. Indian Journal of Experimental Biology. 2008 Sep; 46(9): 677-80en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58026
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.source.urihttps://nopr.niscair.res.in/bitstream/123456789/4581/1/IJEB%2046%289%29%20677-680.pdfen_US
dc.titleIdentification of alpha amylase inhibitors from Syzygium cumini Linn seeds.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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