Assessment of Cardiovascular Disease Risk in Prediabetes

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dc.contributor.authorAgarwal, Ashishen_US
dc.contributor.authorHegde, Anupamaen_US
dc.contributor.authorAhmad, Afzalen_US
dc.contributor.authorYadav, Charuen_US
dc.contributor.authorManjrekar, Poornima A.en_US
dc.contributor.authorRukmini, M. S.en_US
dc.date.accessioned2020-05-05T07:04:51Z
dc.date.available2020-05-05T07:04:51Z
dc.date.issued2020-03
dc.description.abstractThis study was aimed at investigating the nutrient and bioactive components of Annona muricataand Fagara zanthxoyloidefrom south-southern Nigeria. The roots and leaves of these plants were collected from communities within this region and an analysis of the phytochemical, mineral and vitamin components of these plant parts were carried out using standard methods. The results of the investigation revealed the a high presence of alkaloids (27.34 ± 0.15 and 12.98 ± 0.98), flavonoids (19.66 ± 0.04 and 3.71 ± 0.46) and phenols (15.10 ± 0.11 and 0.07 ± 0.42) in the leaves and roots of Annona muricatawhile alkaloids (35.55 ± 0.95 and 50.90 ± 0.83), tannins (28.70 ± 0.19 and 55.37 ± 0.47) and terpenoids (18.23 ± 0.08 and 41.21 ± 0.16) were observed in leaves and roots of Fagara zanthoxyloide. Mineral analysis revealed the presence of iron (20.23 ± 0.01 and 5.21 ± 0.02), calcium (3.67 ± 0.06 and 1.59 ± 0.01), copper (2.17 ± 0.011 and 0.16 ± 0.01) and magnesium (3.04 ± 0.01 and 2.18 ± 0.005) in leaves and roots of Annona muricataand iron, copper (2.53 ± 0.011and 7.38 ± 0.017) and zinc (5.16 ± 0.02 and 5.32 ± 0.011) in leaves and roots of Fagara zanthoxyloide.The leaves and roots of both plants also showed the presence of folate (26.82±0.48 and 23.47±0.03 for A. muricata and 15.82±0.18 and 20.63±0.91 for F. zanthoxyloide) and ascorbate (31.97±0.03and 26.89±0.19 for A. muricataand13.86±0.13 and 30.21±0.01for F. zanthoxyloide) in appreciable quantities while vitamins D, E and K were also observed in minute concentrations in both plant samples. These results may thus suggest that these plants from this region as a result of their rich nutrients and bioactive compositions may play a large role in alleviating the salient nutritional, physiological and medical challenges observed among people within this region.en_US
dc.identifier.affiliationsDepartment of Biochemistry, GS Medical College and Hospital, Pilkhuwa, U.P., Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Kasturba Medical College, Mangalore, MAHE, Karnataka, India.en_US
dc.identifier.affiliationsDepartment of Biochemistry, GS Medical College and Hospital, Pilkhuwa, U.P., Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Lady Harding Medical College, New Delhi, India.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Kasturba Medical College, Mangalore, MAHE, Karnataka, India.en_US
dc.identifier.affiliationsDepartment of Biochemistry, Kasturba Medical College, Mangalore, MAHE, Karnataka, India.en_US
dc.identifier.citationAgarwal Ashish, Hegde Anupama, Ahmad Afzal, Yadav Charu, Manjrekar Poornima A., Rukmini M. S.. Assessment of Cardiovascular Disease Risk in Prediabetes . International Journal of Biochemistry Research & Review. 2020 Mar; 29(2): 1-8en_US
dc.identifier.issn2231-086X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200780
dc.languageenen_US
dc.publisherScience Domain Internationalen_US
dc.relation.issuenumber2en_US
dc.relation.volume29en_US
dc.source.urihttps://doi.org/10.9734/IJBCRR/2020/v29i230166en_US
dc.subjectInterleukin-6(IL-6)en_US
dc.subjectMyeloperoxidase (MPO)en_US
dc.subjectMicroalbuminuria (MA)en_US
dc.subjectcardiovascular risken_US
dc.subjectprediabetesen_US
dc.titleAssessment of Cardiovascular Disease Risk in Prediabetesen_US
dc.typeJournal Articleen_US
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