Ceylon Medical Journal

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    Prevalence of dental fluorosis in four selected schools from different areas in Sri Lanka.
    (1990-09-01) Warnakulasuriya, K A; Balasuriya, S; Perera, P A
    The prevalence of dental fluorosis in four selected schools from different areas in Sri Lanka was investigated by dental examination of 377 school children aged 14 years. In the endemic zone the prevalence of dental fluorosis was 51 to 78% while in a non-endemic area it was 5.4%. There were no significant sex differences in the prevalence of fluorosis. Attention is drawn to the need for using non-fluoridated tooth-paste in areas where dental fluorosis is common. The problem could be further aggravated in the future by the use of water from tube wells in these areas which are known to contain higher concentrations of fluoride than those from shallow wells.
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    An outbreak of measles in the Southern Province.
    (1992-06-01) Lamabadusuriya, S P; Jayantha, U K
    During an outbreak of measles in the Southern Province in 1990, 69 patients were admitted to the Professorial Paediatric Unit of Teaching Hospital Galle. Of these, 13 patients had received the measles vaccination. The commonest complication seen was bronchopneumonia. There were 3 deaths, 2 due to bronchopneumonia and 1 to encephalitis.
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    Our problems of the future.
    (1968-12-01) Cooray, M P
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    Severe systemic effects of Merrem's hump-nosed viper bite.
    (1999-12-15) Kularatne, S A; Ratnatunga, N
    OBJECTIVE: To report unpredictable severe systemic effects of hump-nosed viper envenomation. SETTING: Medical unit, General hospital, Anuradhapura. METHODS: The clinical outcome of seven patients bitten by Merrem's hump-nosed viper were monitored until recovery or death. Limited autopsies were performed on the latter. Offending snakes were positively identified by medical officers and in one instance by a herpetologist. CONCLUSION: Merrem's hump-nosed viper bites, caused an array of potentially fatal systemic manifestations. One patient developed neurological effects, severe Raynaud's syndrome leading to ascending gangrene of distal limbs and adult repiratory distress syndrome (ARDS), in addition to the known complications of severe renal cortical necrosis and haemostatic dysfunction. Two patients who developed acute renal failure and prolonged coagulopathy recovered completely. The combination of extensive renal cortical necrosis, disseminated intravascular coagulation, and ARDS proved fatal in three.
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    Neurology of sleep.
    (1994-03-01) Puvanendran, K
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    Disaster management: lessons from immediate responses to the tsunami.
    (2005-03-11) Samarasinghe, Diyanath
    There are many lessons learnt from the immediate reactions of people in the aftermath of the vast destruction from the giant waves that hit Sri Lanka. Reactions of victims fell between extremes of resilience and helplessness. Responses of those not directly harmed illustrated the two extremes--selflessness and depravity. These responses offer insight into how we live and how we react to situations, and also to an extent how we should be reacting. Among these is that helpers should respect and involve, from the inception, the resources within the group or community affected by the disaster. Control of the relief effort to the maximum feasible extent, should be in the hands of those at whom it is directed.
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    A successful resection of carcinomatous oesophagus.
    (1953-04-01) AUSTIN, L D; COORAY, G H
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    The glass spherical hollow orbital implant: a prospective study.
    (1999-06-24) Stephen, B E
    OBJECTIVE: Various types of orbital implants are in use in the rehabilitation of anophthalmic patients. The latest is the expensive hydroxyapatite implant. The study objective was to evaluate the effectiveness of low cost glass spherical hollow implants, as primary and secondary implants. SETTING: St Michaels and Frazer Private Hospitals, Colombo. STUDY DESIGN AND METHOD: 65 patients had glass sphere orbital implants between 1987 and 1995; 51 primary (evisceration 46, enucleation 5) and 14 secondary (evisceration 2, enucleation 12). At 9 to 12 months follow up, patients were evaluated for mobility of implant, prosthesis mobility, lid sulcus deformity, cosmetic results and complications. RESULTS: Primary glass spherical hollow implants provide excellent mobility of the implant (92%), cosmesis (88%), prosthesis mobility (67%), with a low rate of complications (9.5%). Results of primary implant was superior to that of secondary (p < 0.001). CONCLUSION: Excellent results were obtained with spherical glass spheres as primary implants following evisceration.
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    Primary immune deficiency among patients with recurrent infections.
    (2007-09-21) De Silva, Rajiva; Gunawardena, S; Wickremesinghe, G; Ranasinghe, B; Namasivayam, Y
    OBJECTIVES: Primary immune deficiency is relatively rare. Patients present with recurrent or persistent infections or infections with opportunistic pathogens. We investigated patients who presented during the years 2005-7 with recurrent or persistent infections or infections with opportunistic organisms, for underlying immune deficiency. DESIGN: Descriptive study. SETTING: Department of Immunology, Medical Research Institute, Colombo. STUDY POPULATION: 257 patients referred to the Department of Immunology, Medical Research Institute, Colombo, with a history of recurrent infections, for evaluation of possible immune deficiency. MEASUREMENTS: Appropriate evaluation of immunological competence of the humoral and cell mediated immune systems. RESULTS: There were 8 patients with agammaglobulinaemia (X linked agammaglobulinaemia and autosomal recessive agammaglobulinaemia), 2 patients each with ataxia telangiectasia, IgA deficiency and hyper-IgE syndrome, 3 patients with common variable immune deficiency (CVID), and 1 patient each with Griscelli syndrome, hyper-IgM syndrome and X linked severe combined immune deficiency (SCID). CONCLUSIONS: Primary immune deficiency must be included in the evaluation of patients with recurrent infections, and timely intervention can prevent morbidity and mortality.
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    Apocrine carcinoma of the breast masquerading as a tension cyst.
    (1997-06-01) Angunawela, P; de Silva, M V; Yoheswaran, K
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    Diarrhoea today & tomorrow.
    (1982-12-01) Ranasinghe, L
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    The ability of Ceylonese to taste phenyl thiocarbamide (PTC).
    (1966-09-01) Koch, A C; Nesarajah, M S
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    A trial of deferiprone in transfusion-dependent iron overloaded children.
    (2000-06-29) Lucas, G N; Perera, B J; Fonseka, E A; De Silva, D D; Fernandopulle, M
    OBJECTIVE: To determine the efficacy and safety of deferiprone. DESIGN: Prospective study. SETTING: 5 paediatric medical units at the Lady Ridgeway Hospital for Children (LRHC), Colombo. PATIENTS: Transfusion-dependent iron overloaded children in the age group 2 to 15 years. INTERVENTION: Patients were given a total daily dose of 75 mg/kg of deferiprone orally in divided doses. MEASUREMENTS: Efficacy of deferiprone therapy was assessed by 4-monthly serum ferritin assays using the ELISA technique. Safety of deferiprone therapy was assessed by 4-weekly white cell counts, platelet counts and serum transaminase levels. The Z-test was used to assess the significance of the difference between the mean initial serum ferritin level and the mean subsequent serum ferritin level. RESULTS: 54 patients received deferiprone therapy for a mean duration of 9 +/- 3 months. Initial serum ferritin levels ranged from 1500 to 10,700 ng/ml with a mean of 5743. Subsequent serum ferritin levels, obtained in 48 patients ranged from 740 to 7300 ng/ml with a mean of 3558 (p < 0.001). In 47 of the 48 patients subsequent serum ferritin levels were lower than initial levels. One child developed severe neutropaenia, which reverted to normal on discontinuation of treatment. 11 children developed arthropathy, which responded to ibuprofen therapy combined in some cases with a reduction of the dose of deferiprone to 50 mg/kg/day. Serum transaminase levels were raised in 5 patients but reverted to pretreatment values or lower despite continuation of deferiprone therapy. CONCLUSIONS: Deferiprone is a safe and effective oral iron-chelating agent which can be used, under strict supervision, in transfusion-dependent iron overloaded children.
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    Gluten sensitive enteropathy in a patient with dermatitis herpetiformis.
    (1985-12-01) Harendra de Silva, D G; Chularatne, W; Ravindra Fernando, P
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    The development of vision.
    (1957-05-01) WEEREKOON, L M
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    Laboratory confirmation of dengue and chikungunya co-infection.
    (2008-09-06) Hapuarachchi, H A C; Bandara, K B A T; Hapugoda, M D; Williams, S; Abeyewickreme, W