Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study.

Tanwandee, Tawesak; Piratvisuth, Teerha; Phornphutkul, Kannilka; Mairiang, Pisaln; Permpikul, Parichart; Poovorawan, Yong

Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study.

Date

2006-11-28

Authors

Tanwandee, Tawesak

Piratvisuth, Teerha

Phornphutkul, Kannilka

Mairiang, Pisaln

Permpikul, Parichart

Poovorawan, Yong

Abstract

OBJECTIVE: To investigate the risk of hepatitis C virus (HCV) infection in healthy blood donors in Thailand MATERIAL AND METHOD: We performed a case-control study of 435 HCV-seropositive blood donors and 894 HCV-seronegative blood donors as controls. The study was done with direct interview regarding demographic characteristics and risk factors. Odds ratios (OR) with 95% confidence intervals (CIs) were calculated by using conditional logistic regression. RESULTS: The final multivariable model included only the following independent HCVrisk factors: intravenous drug user (IDU) (OR = 61.5; 95%CI, 26.6-142.5), previous blood or blood products transfusion (OR = 12.3; 95%CI, 7.6 -19.9), sharing of razors (OR = 2.3, 95%CI, 1.6-3.2),unsafe injection (OR = 3.3, 95%CI, 1.8-5.9), unused condom (OR = 1.6; 95%CI, 1.1, 2.4). No risk was shown for a history of tattoo, ear piercing, or acupuncture and multiple sexual partners. CONCLUSION: The risk factors for HCV infection in healthy blood donors in Thailand are IDU, past history of blood transfusion and unsafe injection.

Description

Chotmaihet Thangphaet.

Citation

Tanwandee T, Piratvisuth T, Phornphutkul K, Mairiang P, Permpikul P, Poovorawan Y. Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study. Journal of the Medical Association of Thailand. 2006 Nov; 89 Suppl 5(): S79-83