Cross-sectional Observational Study to Determine Morphology of the Hippocampus in Seizures Disorder by Magnetic Resonance Imaging in a Tertiary Care Hospital
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Date
2024-06
Journal Title
Journal ISSN
Volume Title
Publisher
THE INDIAN MEDICAL ASSOCIATION
Abstract
Background and Objective : Approximately 2-5% of the Worldæ¯ population experiences a seizure in their lifetime and underlying cause which may be revealed by brain MRI. Hippocampus is a structure frequently involved in epilepsy and its morphological imaging is crucial in the diagnostic management of epileptic patients. The objective is to assess the MRI findings in hippocampus with seizures disorder patients. Materials and Methods : The current study is a cross sectional observational study. All patients referred to the Department of Radio-diagnosis with clinically suspected seizures were evaluated with 1.5T Siemens Magnetom Essenza MRI. MR Imaging protocol of seizures was used for evaluation. The changes in hippocampus were evaluated. Conclusion : With its high spatial resolution, excellent inherent soft tissue contrast, multiplanar imaging capability and lack of ionizing radiation, MR imaging has emerged as a versatile tool in the evaluation of patients with seizures. In our study, MRI shows Partial Loss of Hippocampal Striations (PLHS) in 14 cases (23.33%) out of total 60 cases included. MRI also revealed hippocampal atrophy and secondary signs of hippocampal sclerosis in 11 patients (18.33%) out of 60 patients. Hence, we conclude that in our study PLHS in adult population is much more common than the classic signs of hippocampal sclerosis (increased signal intensity and volume loss).
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Keywords
Temporal Lobe Epilepsy, Hippocampal Morphological Changes, Mesial Temporal Sclerosis, Seizures, MRI
Citation
D R Vishwaprem Raj, Salim Khan Mohd Shahid Mohd, D Naveen, C R Srinivasa Babu, B Mallikarjunappa . Cross-sectional Observational Study to Determine Morphology of the Hippocampus in Seizures Disorder by Magnetic Resonance Imaging in a Tertiary Care Hospital. Journal of the Indian Medical Association. 2024 Jun; 122(6): 28-31