Study of Prevalence of Vitamin B12 Deficiency and Hyperhomocysteinemia in Patients of Deep Vein Thrombosis
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Date
2024-01
Journal Title
Journal ISSN
Volume Title
Publisher
THE INDIAN MEDICAL ASSOCIATION
Abstract
Background : Common condition encountered by surgeons are Pulmonary Embolism (PE) and Deep Venous Thrombosis (DVT). About one-third of individuals with symptomatic Venous thromboembolism have PE, whereas the remaining two-thirds exhibit DVT alone. Aims and Objective : To assess the Serum homocysteine & serum Vitamin B12 levels in patients with DVT and to examine the influence of various risk factors on serum homocysteine levels and serum Vitamin B12 levels. Material and Methods : It is a retrospective study conducted in Department of General Surgery, BJ Medical College and Civil Hospital, Ahmedabad from May, 2017 to September, 2018 including 20 Patients. Patients having a DVT diagnosis older than five years were included. Results : Out of 20 patients, Hyperhomocysteinemia was present in 8(40%) and Vitamin B12 Deficiency in 9 (45%) patients. The mean age was 34.6 years & only one female patient (5%). Immobility was present in 6(30%), Smoking history in 8(40%), Cardiac Co-morbidity in 4(20%) Patients. Conclusion : Hyperhomocysteinemia & Vitamin B12 Deficiency are potentially modifiable risk factors that must be considered when evaluating patients for DVT.
Description
Keywords
Deep Vein Thrombosis, Hyperhomocysteinemia, Vitamin B12 Deficiency.
Citation
Barot Mithun Vinod, Bagada Jayeshkumar B, Makwana Rakesh A., Rathod Gunvant H . Study of Prevalence of Vitamin B12 Deficiency and Hyperhomocysteinemia in Patients of Deep Vein Thrombosis. Journal of the Indian Medical Association. 2024 Jan; 122(1): 13-16