Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis

Mullai, Baalaaji; Muralidharan, Jayashree; Karthi, Nallasamy; Singh, Sunit; Bansal, Arun

Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis

Files

ip2018v55n4p311.pdf (586.92 KB)

Date

2018-04

Authors

Mullai, Baalaaji

Muralidharan, Jayashree

Karthi, Nallasamy

Singh, Sunit

Bansal, Arun

Publisher

Indian Academy of Pediatrics

Abstract

Objective: To identify predictors and outcome of acute kidney injury (AKI) in children withdiabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU). Methods:Retrospective case review of 79 children with DKA admitted between 2011-2014. Results: 28children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone.Serum chloride at 24 hours was independently associated with AKI. Children with AKI hadprolonged acidosis, longer PICU stay, and higher mortality. Conclusions: Majority of childrenwith AKI and DKA recover with hydration. Hyperchloremia at 24 hours had independentassociation with AKI, although cause-effect relation could not be ascertained.

Keywords

Diabetes, Hyperchloremia, Outcome, Renal failure

Citation

Mullai Baalaaji, Muralidharan Jayashree, Karthi Nallasamy, Singh Sunit, Bansal Arun. Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis. Indian Pediatrics. 2018 Apr; 55(4): 311-314

URI

https://imsear.searo.who.int/handle/123456789/199064

Collections

Indian Pediatrics

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