A Study of Clinical Profile of Patients with Febrile Thrombocytopenia
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Date
2019-03
Journal Title
Journal ISSN
Volume Title
Publisher
Society for Health Care & Research Development
Abstract
Febrile thrombocytopenia is one of the unrecognized complication which may be missed if platelet count is not done routinely. Increased awareness and early recognition of thrombocytopenia can avoid catastrophes like fatal bleed. The aim of study is to find clinical presentation of patients with febrile thrombocytopenia and find causes and complications associated with febrile thrombocytopenia. Methods: In the present study 107 patients who presented to Shri B. M. Patil Hospital with fever with thrombocytopenia who fulfil inclusion criteria are included in study, a detailed history general physical examination, investigations were performed and patients were treated symptomatically and specifically after diagnosis. Results: In the present study subjects were in the age group of 18-80 years. Youngest was 18 years old and oldest 80 years. In the present study out of 107 cases of fever with thrombocytopenia, 79 were males and 28 were females. Out of 107 patients of fever with thrombocytopenia, 102 had definitive diagnosis with Dengue 54 cases as the commonest cause, followed by Malaria which constituted 40 cases, Mixed infections 3 cases(Dengue fever with enteric fever, Vivax malaria, falciparum malaria), Acute Gastroenteritis 2 cases, Urinary tract infections 1 case, Leptospirosis 2 cases and Enteric fever 2 cases and Unknown causes accounted for 5 cases. In our study 61 patients had platelet count less than 60,000 cells/cumm, whereas 46 had above 60,000 cells/cumm. Common range of platelet count was from 41,000 – 60,000 cells/cumm in 27 cases.Of 107 patients 104 of them recovered and 3 expired with mortality of 2.8% with All 3 patients had MODS. Conclusion: In all cases of Febrile thrombocytopenia, thrombocytopenia led to various bleeding manifestations and influenced the clinical profile of these illnesses. Petechiae were the most common bleeding manifestation. The spectrum varied from mild self-limiting disease to severe fatal disease. This highlights the need for rapid diagnosis and appropriate management of patients to prevent complications.
Description
Keywords
Platelet Count, Thrombocytopenia
Citation
Magdum Nikhil, Warad Vijaykumar, Devarmani S S, Kattimani Ravi. A Study of Clinical Profile of Patients with Febrile Thrombocytopenia. Annals of International medical and Dental Research. 2019 Mar; 5(2): 6-13