High-Density Lipoprotein as a Therapeutic Target: Treatment Strategies.
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Date
2012
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Abstract
Coronary artery disease (CAD) is one of the most important causes of morbidity and mortality
worldwide despite considerable therapeutic advances that control the risk factors. Numerous clinical
trials have shown an inverse association between high density lipoprotein cholesterol levels and the
risk of coronary artery disease. So, high density lipoprotein has become a new therapeutic target
after low density lipoprotein in the management of risk factors of coronary artery disease. In this
review, we explore existing and future treatment strategies along with their benefits and failures
which will guide our management strategy. HDL raising therapies showed very promising results
in many clinical trials but larger clinical trials are ongoing.
Description
Keywords
High density lipoprotein, Coronary artery disease
Citation
Chowdhury M A U, Ali S Y, Rahman M M, Islam A E M M, Islam A K M M. High-Density Lipoprotein as a Therapeutic Target: Treatment Strategies. Cardiovascular Journal. 2012; 5(1): 73-80.