Iodide transport in isolated cells of mouse submaxillary gland.
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Date
1986-09
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Abstract
A method has been developed to isolate cells from the submaxillary gland of
mouse by treatment with pronase. Three fractions of cells have been isolated having
almost equal iodide concentrating activity. The isolated cells show time dependent uphill
transport of iodide. The transport is substrate-saturable, having a Km value of 0·3 μΜ for
iodide. The transport is sensitive to antithyroid drugs, metabolic inhibitors and to some
extent to ouabain. Pseudohalide such as thiocyanate competes with the transport of
iodide. Thyroid hormones or thyroid stimulating hormone have no significant effect on the
iodide transport in these cells.
Description
Keywords
Iodide transport, iodide concentration, isolated cells of submaxillary gland
Citation
Banerjee P K, Bose A K, Chakraborty T K, De P K, Datta A G. Iodide transport in isolated cells of mouse submaxillary gland. Journal of Biosciences. 1986 Sept; 10(3): 303-309.