Genito-urinary tuberculosis revisited - 13 years' experience of a single centre.
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Date
2013-01
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Abstract
Background: Tuberculosis had been declared by the World Health Organization (WHO) as ‘public health emergency’ in
1993. Extra pulmonary tuberculosis (E.P.T.B.) comprises 20-25% total burden of the disease in which genitourinary
tuberculosis (G.U.T.B.) is 4%. Timely diagnosis and treatment will prevent the sequelae of this disease.
Aims: To know the varied clinical presentations, diagnostic modalities and management of G.U.T.B.
Methods: During a 13-year-period, 117 retrospective cases of GUTB were admitted in the tertiary care centre. They were
analyzed for clinical presentation, diagnostic modalities and management.
Results: Young patients mainly in third decade of life were commonly affected with higher incidence in females. In our study,
the most common presentation was irritative voiding symptoms (66.47%) followed by haematuria (47.60%). Although it
can affect the entire organ in genito-urinary system but, in the present study, kidney was the most affected organ (64.9%)
following ureter (27.35%), urinary bladder (17.09%), prostate (3.4%) and epididymis (5.19%). In this study, we had not
encountered any case of testicular and penile tuberculosis. Among the different diagnostic modalities in this study, the
diagnostic positivity rate was 41.6% for the urine AFB test, 55.4% for the urine M. tuberculosis culture test and 67.7% for
PCR. Chest x-ray was positive in 25.6% (30). ESR was raised in 62.5% and Mantoux test was positive in 61.2% patients.
Conclusion: A high index of suspicion and a wide range of investigations may be required to achieve a complete
diagnosis of genitourinary tuberculosis. Though short course chemotherapy with four-drug-regimen for sixmonth-
duration is the mainstay of treatment, surgical interventions were required in 60% of cases of this
study.
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Keywords
Chemothearpy, Genito-urinary, Genito-urinary, Tuberculosis
Citation
Singh Jitendra P, Priyadarshi Vinod, Kundu A K, Vijay M K, Bera M K, Pal D K. Genito-urinary tuberculosis revisited - 13 years' experience of a single centre. Indian Journal of Tuberculosis. 2013 Jan; 60(1): 15-22.