Phytochemical Analysis and Cardiac Depressant Activity of Aqueous Methanolic Extract of Morus nigra L. Fruit.
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Date
2012-12
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Abstract
The present study was conducted to investigate the effects of aqueous methanolic extract of Morus nigra L.
fruiton frog’s heart.Force of contraction and heart rate were measured by force displacement transducer attached
to Power Lab data acquisition system. Lab chart Pro 5 software was used for the acquisition and analysis of data.
The extract was also screened for various phytochemical constituents using standard methods. The results
indicated that the extract produced a significant dose dependent decrease in heart rate without affecting the
contractility of the heart. Phytochemical analysis also revealed that the extract contained flavonoids, cardiac
glycosides,alkaloids, saponins and phenolic compounds.It is conceivable therefore; that the negative chronotropic
effectsof aqueous methanolic extract of Morus nigra L. fruit may be attributed to the presence of certain
pharmacologically active compounds.
Description
Keywords
Morus nigra L., Cardiovascular, Phytochemical, Frogs
Citation
Malik Muhammad Nasir Hayat, Alamgeer, Salma Ume, Qayyum Abdul, Samreen Sadia. Phytochemical Analysis and Cardiac Depressant Activity of Aqueous Methanolic Extract of Morus nigra L. Fruit. Journal of Applied Pharmaceutical Science. 2012 Dec; 2(12): 39-41.