A 10-year experience of managing acute limb ischaemia in India.
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Date
2008-11
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Abstract
Background. Acute limb ischaemia is threatening to both
limb and life. There is little information about this disease
entity from India.
Methods. We did a retrospective analysis of the clinical
profile of patients presenting with non-traumatic acute limb
ischaemia to our department (a tertiary care centre in India)
from January 1998 to December 2007. The demography, risk
factors, time taken to present to the emergency from the onset
of symptoms, time taken to administer the first dose of heparin
upon arrival to the emergency, primary interventions and
outcomes in terms of amputation rates and in-hospital mortality
were studied.
Results. The mean (SD) age of the 84 patients was 48.9
(14.3) years. Only one patient died (1.2%) and 24 patients
had an amputation (28.6%). Among the predisposing risk
factors a significant association was found between smoking
and the rate of amputation. Early presentation to emergency
and early administration of heparin was associated with lower
amputation rates though this did not achieve statistical
significance.
Conclusion. Acute limb ischaemia is a catastrophic event.
Smoking is a risk factor associated with poorer outcomes. Early
arrival to the emergency and early administration of heparin
was associated with lower amputation rates.
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Turel Mazda, Kumar Prabhu Prem, Stephen Edwin, Agarwal Sunil. A 10-year experience of managing acute limb ischaemia in India. National Medical Journal of India. 2008 Nov-Dec; 21(6): 284-287.