Free estrogens and progestogens in benign prostatic hypertrophy.

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Date
1985-04-01
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Abstract
Studies on the presence of free estrogens and progestogens in human prostates clearly differentiate the benign hypertrophied prostates from normals. Both contained 17 alpha-hydroxypregnenolone 5 beta-pregnane-3, 20-dione, 5 alpha-pregnane-3, 20-dione and 16 alpha-hydroxyestrone. However, presence of 11 alpha-hydroxyprogesterone 20 beta-hydroxypregnenolone, pregnenolone, 17 alpha-hydroxyprogesterone, as well as estrone and estriol exclusively in BPH samples pointed to their possible involvement in the development of benign prostatic hypertrophy.
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Narayan JP, Srivastava SP, Singh JN. Free estrogens and progestogens in benign prostatic hypertrophy. Indian Journal of Physiology and Pharmacology. 1985 Apr-Jun; 29(2): 119-22
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https://imsear.searo.who.int/handle/123456789/107330
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Indian Journal of Physiology and Pharmacology