Tissue sensitivity to acetylcholine, adrenaline, noradrenaline and serotonin and agents acting on sulphydryl groups.

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1984-04-01
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Abstract
Parachloromercury benzoate (PCMB), a sulphydryl inactivator, caused a progressively increasing inhibition of tissue responses to acetylcholine, adrenaline, noradrenaline and serotonin in vitro. This inhibition was progressively and completely reversed by penicillamine, a sulphydryl activator. It is inferred that intact sulphydryl groups are essential for constancy of responses of excitable tissues to the neurotransmitters.
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Tongia SK, Pandya K. Tissue sensitivity to acetylcholine, adrenaline, noradrenaline and serotonin and agents acting on sulphydryl groups. Indian Journal of Physiology and Pharmacology. 1984 Apr-Jun; 28(2): 141-4