Indian Journal of Gastroenterology
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Item 111Indium leukocyte scanning: is it a useful clinical tool?(1986-01-01) Gupta, SItem 14C-urea breath test for assessment of gastric Helicobacter pylori colonization and eradication.(2001-07-11) Tewari, V; Nath, G; Gupta, H; Dixit, V K; Jain, A KBACKGROUND AND OBJECTIVE: Urea breath test (UBT) is a reliable noninvasive technique for detecting gastric Helicobacter pylori colonization. 14C isotope-based test requires simple equipment and is inexpensive. We studied the utility of 14C-UBT in diagnosis of gastric H. pylori infection. METHODS: Presence of H. pylori was studied using antral histology and culture in patients with rapid urease test (RUT)-positive peptic ulcer. 14C-UBT was performed using a 185-kBq dose. Radioactivity in 15-min breath samples was measured using a beta-scintillation counter and result expressed as % dose recovered/mmol CO2. H. pylori was considered positive when any two tests were positive. All tests were repeated one month after completion of H. pylori eradication therapy. RESULTS: Among 41 patients (duodenal ulcer 36, gastric ulcer 5), H. pylori was detected by histology in 23 (56%) and by culture in 27 (66%). Overall, H. pylori was detected in 28 (68%) patients. Follow-up assessment was possible in 28 patients: 26 cleared the infection (all three tests negative). Mean 14C recovery values at 15 minutes associated with H. pylori-positive status were significantly higher (12.3 [SD 6.8] x 10(-3); n=30; p<0.001) than those associated with H. pylori-negative status (2.1 [0.9] x 10(-3); n=26). Using receiver-operating-characteristic analysis of 15-minute 14C recovery values, a cut-off of 6.5x10(-3) gave the best separation of H. pylori-positive and -negative cases. 14C-UBT had 93% sensitivity, 96% specificity and 95% accuracy. CONCLUSION: 14C-UBT appears to be a reliable noninvasive test for diagnosis of H. pylori infection.Item 2nd annual conference, UP State Chapter, Indian Society of Gastroenterology; King George's Medical College, Lucknow; March 8-9, 1991.(1991-07-01) Kapoor, V K; Aggarwal, RItem 3, 6 or 9–band shooters: tailor made ligators as needed.(2011-07) Nijhawan, Sandeep; Gupta, Gaurav; Sharma, Anil; Mathur, Amit; Sapra, Bharat; Nepalia, SubhashItem 40,244 stones in a gallbladder.(1988-10-01) Sachdev, A K; Misra, P K; Choudhary, A; Salunkhe, S D; Aranya, R CItem 99m-technetium-phytate scanning in the diagnosis of hepatic hydrothorax.(1987-10-01) Plumber, S T; Popat, N; Bhambure, N; Tilve, G H; Naik, S RItem Abdominal cocoon causing small bowel obstruction.(1987-01-01) Bhatnagar, A; Pathania, O P; Malik, V; Chowdhry, AItem Abdominal cocoon--the cauliflower sign on barium small bowel series.(1995-01-01) Navani, S; Shah, P; Pandya, S; Doctor, NWe report a case of abdominal cocoon encasing the small bowel diagnosed pre-peratively on radiology. Barium small bowel series showed the ileal loops clumped together as within a sac, giving a cauliflower-like appearance on sequential films. At surgery, the membrane enclosing the loops was thin and flimsy.Item Abdominal mass with significant family history.(2008-07-01) Chandrasekar, T S; Shanmugam, Subbiah; Lawrence, Radhi; Abraham, PhilipItem Abdominal tuberculosis: the Indian contribution.(1998-10-31) Kapoor, V KItem Abdominal wall abscess secondary to subcapsular tubercular liver abscess.(2003-09-09) Desai, Nutan; Patil, Shivanand; Thakur, Bhagwan Singh; Das, Haribhakti Seba; Manjunath, S M; Sawant, PrabhaWe report a 22-year-old woman who presented with an abdominal wall lump in the right upper quadrant 15 days after starting antitubercular treatment for right pleural effusion. CT scan revealed a right liver lobe subcapsular abscess communicating vith subcutaneous tissue. Aspiration of pus revealed acid-fast bacilli. She responded to 9 months of antitubercular treatment.Item Absence of Mycobacterium avium ss paratuberculosis-specific IS900 sequence in intestinal biopsy tissues of Indian patients with Crohn’s disease.(2009-09) Sasikala, Mitnala; Reddy, D Nageshwar; Pratap, Nitesh; Sharma, Sanjeev Kumar; Reddy, P Balkumar; Sekaran, Anuradha; Banerjee, Rupa; Reddy, D BhaskaraBackground and Objective The role of Mycobacterium avium ss paratuberculosis (MAP) in the etiopathology of Crohn’s disease (CD) remains controversial, because of conflicting reports demonstrating the presence of MAP-specific insertion sequence from intestinal biopsy tissues of patients clinically diagnosed for the disease. The present study was carried out to investigate the presence of MAP DNA in the intestinal tissues of CD patients to ascertain the relevance of MAP in Indian patients with CD. Methods Patients diagnosed as CD at our institute were recruited. Healthy individuals without inflammatory bowel disease served as controls. Mucosal biopsy specimens were collected from ileum and colon in duplicates and subjected to histopathological examination and polymerase chain reaction (PCR) amplification. Total DNA (81 CD patients, 85 healthy individuals) and total RNA (12 CD patients, 12 healthy individuals) isolated from tissue specimens was used for amplification of MAP-specific IS900 by nested PCR. Results MAP-specific IS900 DNA and RNA could not be detected by nested PCR in the intestinal tissues of any patient with CD. Conclusion Our results do not support the etiological role of MAP in the pathogenesis of CD in Indian patients.