International Journal of Medical Research Professionals

Permanent URI for this collection

https://imsear.searo.who.int/handle/123456789/163903

Editor-in-Chief: Dr. Rohin Garg
ISSN: 2454-6356 (Print); 2454-6364 (Online)

Frequency: Bimonthly

Language: English

Open Access Peer-reviewed journal

Web site: https://ijmrp.com/Default.aspx

Browse

Browsing International Journal of Medical Research Professionals by Subject "Acetaminophen"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Comparison Between the Efficacy of Acetaminophen and Ibuprofen for Relieving Orthodontic Pain
    (Ibn Sina Academy of Medieval Medicine & Sciences, 2019-03) Chaturvedi, Mohit; Chaturvedi, Neha
    Background: Postoperative pain is most commoncomplication after orthodontic therapy. Non-steroidal antiinflammatory drugs are among most widely prescribedanalgesics for management of postoperative pain. The aim ofthe present study was to compare the efficacy ofacetaminophen and ibuprofen for relieving orthodontic pain.Materials and Methods: A sample of 40 patients who neededfixed orthodontic therapy was selected for this study. Beforethe commencement of the study informed consent was takenfrom all patients. Patients who were scheduled for fixedorthodontic treatment with age more than 16 years wereselected for the study. Patients with presence of any systemicdisease, patients contraindicated to use of NSAID, patientsusing any antibiotics or analgesics were excluded from study.The three drugs i.e., Acetaminophen, Ibuprofen, Placebo wererandomly administered among patients in each age category.Mclaughlin, Bennett, Trevisi (MBT) 0.022” slot and 0.016” NiTiinitial aligning wire were used for patients with mild ‑ to ‑moderate crowding. Each patient was thereafter asked to notethe degree of pain perceived at specific intervals of time (1hour, 1day; and 7th day), during chewing and biting. Statisticalanalysis was done by using SPSS, version 22 (SPSS, Inc.,Chicago, IL) and p<0.05 was considered statisticallysignificant.Results: A total of 40 patients were included in the study inwhich 16 were male whereas 24 were females. Analgesicdrugs were distributed among groups; to group I Ibuprofenwas given which include 7 males 11 females, to group IIAcetaminophen was given which include 5 males and 8females, to group III Placebo were given which include 4 malesand 5 females. For both chewing and biting there is nosignificant difference between Group I and group II , but thereis significant difference between group I and II with respect toGroup III until 7th day.Conclusion: Our study concluded that preoperativeadministration of acetaminophen and ibuprofens were effectiveto control the postoperative pain. However, acetaminophen canbe considered as the treatment of choice due to the fact that itdoes not cause gastrointestinal (GI) ulcers.