Browsing by Author "Tripathi, A."

Now showing 1 - 7 of 7
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    Comparison between intraoperative and postoperative surgical outcomes of laparoscopic partial nephrectomy and open partial nephrectomy: laparoscopic versus open partial nephrectomy
    (Medip Academy, 2023-12) Sharma, S.; Swain, S.; Panda, S.; Tripathi, A.; Yash Manharlal, T.; Behera, K. K.; Anshuman, J.
    Background: The aim of the study was to compare intraoperative and postoperative surgical outcomes of laparoscopic partial nephrectomy (LPN) and open partial nephrectomy (OPN). Methods: We did prospective retrospective study on 33 cases of renal mass operated as partial nephrectomy (PN) (15 LPN and 18 OPN) in department of urology and renal transplant SCB medical college Cuttack Odisha from 1 may 2019 to 1 may 2023. Surgical outcome of both approaches compared based upon intraop time, estimated blood loss, ischemia time, hospital stay, complications and rise in creatinine. Results: Mean intraop time 140.66 min in OPN vs 172.8 min in LPN (p<0.05-significant), mean estimated blood loss was 453 ml in OPN vs 345 ml in LPN (p=0.113-not significant), mean ischemia time was 15.88 min in OPN vs 20.53 min in LPN (p<0.05-significant), mean post op hospital stay was 7.5 days in OPN vs 6.3 days in LPN (p=0.184-not significant). Intra-op complications was 2 (11.11%) in OPN vs 2 (13.33%) in LPN and postop complications was in 5 (27.7%) in OPN vs 4 (26.66 %) in LPN. Mean rise in creatinine was 0.25 in OPN vs 0.29 in LPN (p=0.642-not significant). Conclusions: LPN is a feasible and safe alternative to OPN with comparable surgical outcomes but operating time and ischaemia time is significantly more in LPN as compare to OPN.
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    An Evaluation of Beta-Lactamase Prevalence and the Increasing Incidence of MBL in Gram-Negative Bacteria.
    (Light House Polyclinic, 2024-12) Joshi, A; Nirkhiwale, N; Bhasin, S; Tripathi, A.
    Purpose: ?-lactamase mediated resistance mechanisms in gram-negative bacteria play a pivotal role in spreading antimicrobial resistance. We conducted this study to understand the prevalence of ?-lactamases in Gram-negative bacteria in our region. Methodology: We conducted a cross-sectional study that included 3710 clinical specimens for culture tests from 2021 to 2023 following standard CLSI guidelines. Result: Extended spectrum ?-lactamase resistance was the leading antimicrobial resistance mechanism detected in 53% E. coli isolates, followed by metallo ?-lactamases (14%). Klebsiella pneumoniae was the second most predominant organism isolated, where 28% isolates exhibited metallo ?-lactamase-mediated resistance. Comparative analysis of resistance levels in 2021 and 2022 revealed an increase in the prevalence of MBL resistance by 33% in K. pneumoniae. The prevalence of MBL producing P. aeruginosa increased by 51% from 2021 to 2022. Conclusion: The comparative resistance analysis between 2021 and 2022 highlights the impact of COVID-19 on the expedited rise of antimicrobial resistance.
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    Generalized Estimating Equation In Pharmacological Study
    (Mahadev Publications, 2018-05) Tripathi, A.; Bora, M.; Dr Lalrinpuia; Mukherjeeherjee, K.; Upadhaya, S. N.
    Generalized Estimating Equation (GEE) deals with such data that do not have normal distribution in case of repeated experiment and has better properties as compared to rANOVA. With the objective to describe the use of GEE in pharmacological study this endeavour started. GEE described hereby using rat data. Four correlation structured were taken in GEE. It was found Independent/Exchangeable structure best suited with data. The model fit on data was assessed graphically as well. The trend line of repeated data for all cases (rats) were fallen in 95 % bound of predicted model. The model gave the average weight of rat 226.51 gram with start of experiment and it increases 8.67gram per week after feeding high fat diet.
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    Premature presbyopia: causes, diagnosis, and management strategies - an overview
    (Medip Academy, 2024-06) Sonali, K. M.; Dubey, G.; Pant, K.; Tripathi, A.; Yadav, P.
    Premature presbyopia refers to the early onset of age-related vision changes typically associated with presbyopia, a condition characterized by the loss of near vision accommodation. This review article aims to provide an overview of the causes, diagnosis, and management strategies for premature presbyopia. The database collected from PubMed, PubMed Central (PMC), Cochrane library, and Google scholar and research gate. This review discusses the potential underlying mechanisms contributing to premature presbyopia, including genetic factors, environmental influences, and ocular conditions. Additionally, the diagnostic criteria and assessment methods used to identify premature presbyopia and differentiate it from other vision disorders. Finally, this review examines various management options for premature presbyopia, including corrective lenses, pharmacological interventions, surgical procedures, and emerging treatments. By understanding the factors contributing to premature presbyopia and implementing appropriate management strategies, healthcare professionals can effectively address the needs of individuals experiencing early onset age-related vision changes.
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    Removal of methylene blue azo dye from aqueous solution using biosorbent developed from floral waste
    (Triveni Enterprises, 2024-01) Agarwal, S.; Rana, N.; Bhardwaj, P.; Tiwari, G.N.; Yadav, A.K.; Garg, M.C.; Mathur, A.; Tripathi, A.
    Aim: The present study was carried out to prepare biosorbent from temple floral waste (Tagetes erecta) by pyrolysis and chemical activation method for removal of methylene blue dye from aqueous solution. Methodology: Floral waste of Tagetes erecta collected from the temples were segregated, washed and dried to form biochar by direct pyrolysis and chemical activation method. Followed by physio-chemical analysis of biosorbents the most efficient biochar was selected for the removal of methylene blue dye from aqueous solution. The adsorbent efficiency and percentage removal of methylene blue dye was studied using various doses of biochar (10, 20, 30, 40, 50, 60, and 70 mg 100 ml-1,), effect of pH (2.0 to 4.0, 6.0 to 8.0, and 10.0 to 12.0) and effect of contact time etc. Results: The comparative physio-chemical analysis of the bio chars suggested that the activated charcoal made from temple flower waste by the direct pyrolysis method showed better performance, with its low moisture content (5.3%), low ash content (4.3%), higher yield, larger surface area, and higher porosity (65.3%) as compared to the biochar obtained from chemical activation. The percent adsorption significantly increased (p<0.05) from 76% to 87.0% on increasing biochar dose from 10.0 to 70.0 mg 100 ml-1. On increasing the pH of the solution from 4.0 to 6.0, Methylene blue removal significantly increased (p<0.05) from 88.0% to 91.0%. Interpretation: It is possible to manage floral waste from temples in a sustainable and environmentally responsible manner by converting it into biochar and using it for the treatment of waste water in order to eliminate hazardous dyes.
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    Renal artery variants: a comprehensive cadaveric comparative study using morphological and corrosion casting technique
    (Medip Academy, 2024-04) Kaushik, R. K.; Tripathi, A.; Kausar, H.; Goel, P.; Raizaday, S.; Dawani, P.
    Background: Kidneys, crucial excretory organs, receive substantial blood supply through renal arteries. Variations in their anatomy are common, warranting detailed investigation. This study aims to comprehensively examine renal artery patterns using both gross dissection and the corrosion cast method. Methods: Thirty kidney pairs from cadavers were meticulously dissected at Subharti Medical College, Meerut, U.P. India. Gross features were carefully noted, and corrosion casts were meticulously prepared. Prevalence, origin, level, division, course, and variations were exhaustively recorded to provide a thorough understanding of renal vascular anatomy. Results: Main renal arteries were found to predominantly originate from the abdominal aorta in all specimens. Interestingly, a higher prevalence of origin of right renal arteries was observed, with 47% exhibiting a higher origin than their left counterparts. Further analysis revealed prehilar division in 38.3% and hilar division in 61.6% of specimens. Notably, a segmental pattern of renal arteries was observed. Accessory renal arteries (8%) were identified, including rare occurrences of bilateral and double accessory renal arteries. Of particular significance was the observation of an accessory renal artery passing anterior to the inferior vena cava, highlighting the intricacies of renal vascular variations. Conclusions: While reaffirming the conventional understanding of renal arterial anatomy, this study emphasizes the complexity and clinical relevance of variations in renal artery morphology. Such detailed insights are invaluable for surgical and radiological practice, underlining the importance of meticulous preoperative assessment to optimize patient outcomes.
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    Therapeutic Outcomes of Mucormycosis Patients: A Retrospective Cohort Study
    (Journal of Indian Medical Association, 2025-02) Gupta, N; Karoli, R; Verma, P; Shakya, S; Singh, M; Pathak, A; Tripathi, A.
    Introduction: Of all the cases of mucormycosis across the world, India has the largest number, probably because of the large number of uncontrolled diabetes mellitus and its climate, which favors mucormycosis. There is still scarce data in India regarding the duration of treatment required and factors associated with the outcome, such as the extent of disease, glycemic control, hematological, and biochemical parameters. Therefore, this study aims to study any association between the extent of disease and outcome, and the association of hematological and biochemical parameters with the outcome of the disease. Materials and methods: It was a retrospective cohort study. Study patients were all mucormycosis patients admitted from May 2021 to October 2021 in the Department of Medicine in a tertiary care teaching hospital. Diagnosis was made by direct KOH microscopy, histopathology, or fungal culture from nasal tissue. Patients who showed mixed infections or were on iron supplementation were excluded. Results: One hundred patients were included, of which 82 were cured and 18 expired. Of the 18 expired, 12 had rhino-orbito-cerebral mucormycosis (ROCM) and 6 had rhino-orbital mucormycosis. The mean age was 51.12 years and the mean body mass index (BMI) was 25.02 kg/ m². The most common comorbidity was diabetes mellitus (85%). The mean duration of antifungals given until the cure of the patient was 30.05 ± 8.34 weeks. Mean hemoglobin and serum iron were low, and serum ferritin was elevated. Facial pain, facial swelling, nasal discharge, decreased vision, and periorbital swelling were the most common presenting symptoms of mucormycosis, and these persisted for a mean duration ranging from 16 to 28 days. Conclusion: Rhino-orbital mucormycosis was the most common type of mucormycosis. Uncontrolled diabetes mellitus was the most common comorbidity associated with mucormycosis, so it should be treated properly. The mean duration of antifungals given until the cure of the patient was 30.05 ± 8.34 weeks. There was no significant association between the duration of antifungals and glycated hemoglobin (HbA1C), serum ferritin, or type of mucormycosis.