Browsing by Author "Raghavan, V"

Now showing 1 - 13 of 13
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    CGH titres in clomiphene induced pregnancies.
    (1973-07-01) Vaidya, P R; Purandare, B N; Rao, S S; Raghavan, V
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    Congenital hernia through the foramen of Morgagni (a case report).
    (1990-04-01) Sortey, D D; Mehta, M M; Jain, P K; Agrawal, S R; Gadkari, S M; Raghavan, V; Bhansali, S K
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    Development and validation of a questionnaire to measure preferences and expectations of patients undergoing palliative chemotherapy: EXPECT questionnaire.
    (2016-04) Patil, VM; Chakraborty, S; Jithin, TK; Dessai, S; Babu, TP Sajith; Raghavan, V; Geetha, M; Kumar, T Shiva; Biji, MS; Bhattacharjee, A; Nair, C
    OBJECTIVE: The objective was to design and validate the questionnaire for capturing palliative chemotherapy‑related preferences and expectations. DESIGN: Single arm, unicentric, prospective observational study. METHODS: EXPECT questionnaire was designed to capture preferences and expectations of patients undergoing palliative chemotherapy. This questionnaire underwent a linguistic validation and then was tested in patients. Ten patients are undergoing chemotherapy for solid tumors who fulfilled the inclusion and exclusion criteria self‑administered the EXPECT questionnaire in regional language. After filling this questionnaire, they self‑administered quick questionnaire‑10 (QQ‑10). SPSS version 16 (IBM New York) was used for analysis. Completion rate of EXPECT questionnaire was calculated. The feasibility, face validity, utility and time taken for completion of EXPECT questionnaire was also assessed. RESULTS: The completion rate of this questionnaire was 100%. All patients completed questionnaire within 5 min. The QQ‑10 tool confirmed the feasibility, face validity and utility of the questionnaire. CONCLUSION: EXPECT questionnaire was validated in the regional language, and it’s an effective tool for capturing patient’s preferences and expectation from chemotherapy.
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    Development of an enzyme-linked immunoassay for human chorionic gonadotropin.
    (1977-06-01) Joshi, U M; Raghavan, V; Sheth, A R
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    Effect of weaning on gonadotropin levels in plasma & pituitary of female mice.
    (1982-03-01) Raghavan, V; Sheth, P R; Nandedkar, T D; Sheth, A R
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    Endometriosis Unveiled: A Series on Diverse Clinical Presentations and Synchronous Pathologies.
    (Light House Polyclinic, 2024-07) Raghavan, V; Srinivasan, S; Srivastava, S
    Abstract: Endometriosis is a prevalent gynecological condition affecting women of reproductive age and is often associated with infertility. The role of chronic inflammation as a significant etiological factor is supported by the frequent co-occurrence of conditions such as salpingitis isthmic nodosa in our case series. In this study, we present a rare case of synchronous endometriosis and Enterobius vermicularis infection in the ovary, underscoring the necessity for clinicians to consider diverse etiologies and pathologies in their diagnostic and treatment approaches. This case series emphasizes the importance of recognizing the varied presentations and potential complications of endometriosis to improve patient outcomes.
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    Ethical challenges faced by community mental health workers in urban Chennai
    (FORUM FOR MEDICAL ETHICS SOCIETY, 2022-12) Raghavan, V; Sanjana, G
    Background: Delivery of mental health interventions to youth in schools requires a cadre of community mental health workers (CMHWs) in addition to psychiatrists. Literature is sparse in the India context on the ethical and professional challenges faced by CMHWs, especially those working with youth. Hence, the aim of the study was to understand these challenges faced by CMHWs working in schools in urban Chennai and explore ways to overcome them. Methods: A qualitative study was done with CMHWs involved in the delivery of youth mental health (YMH) interventions, including mental health literacy, screening for mental disorders and mental health support to youth in schools in urban Chennai. Focus group discussions (FGDs) were conducted with the study participants and audio recorded. Transcription of the recording was done verbatim and coded for themes using a thematic analysis approach. Results: Two FGDs were conducted with a total of eight participants. The mean (± standard deviation) age of the participants was 27 ± 3.7 years; all having a master’s degree in either psychology, social work, or public health. The major themes that emerged were the meaning of ethics and professionalism, confidentiality, dilemma in decision making, incongruence between the requirements of student and school administration, and personal and professional challenges faced by CMHWs. Recommendations to overcome these challenges were also explored. Conclusion: The results indicate CMHWs face significant ethical challenges with confidentiality, and decision making while delivering YMH interventions in schools, highlighting the need for designing and implementing a framework to address these challenges.
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    Human chorionic gonadotropin levels during pregnancy in Indian women.
    (1973-02-01) Raghavan, V; Rao, S S; Chaubal, U; Punjabi, J; Krishna, U
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    Navigating Diagnostic Challenges in Cutaneous Leiomyosarcoma: A Clinical Case Study.
    (Light House Polyclinic, 2024-07) Raghavan, V; Sithika, AT; Chandrasekaran, K
    Abstract: Cutaneous Leiomyosarcomas (CL) are rare, constituting just 3% of malignant soft tissue sarcomas. We present a case involving a 40-year-old male with a forearm nodule. Histopathological examination revealed atypical spindle cells with immunohistochemistry confirming Cutaneous Leiomyosarcomas. While the patient had a prior excision for a similar swelling, reports were unavailable. Treatment involved a wide resection with a lesion-free specimen. Cutaneous Leiomyosarcomas commonly presents as a nodular growth in extremities, with a microscopic appearance characterized by spindle-shaped cells exhibiting palisading and atypia. Differential diagnoses include other spindle cell lesions necessitating IHC for confirmation. Recurrence rates underscore the importance of wide excision. Distant metastasis, primarily to the lungs, and identified prognostic factors, such as lesion size and histological grade, contribute to the complex clinical landscape. This case emphasizes the rarity of Cutaneous Leiomyosarcomas, emphasizing the need for thorough diagnostic evaluation and a multidisciplinary approach for effective management.
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    Patterns of care in geriatric cancer patients – An audit from a rural based hospital cancer registry in Kerala.
    (2015-01) Patil, V M; Chakraborty, S; Dessai, S; Kumar, S S; Ratheesan, K; Bindu, T; Geetha, M; Sujith, K; Babu, S; Raghavan, V; Nair, C K; Syam, V; Surij, S; Sathessan, B
    BACKGROUND: There is deficit of data from India on elderly patients with cancer. Comprehensive geriatric assessment may lead to a better decision making capacity in this population. However, routine implementation of such assessment is resource consuming. AIM: The aim of this study was to determine the patterns of care in elderly patients treated at a tertiary rural cancer center in India. MATERIALS AND METHODS: All patients with age 70 or above with solid tumors without any definitive treatment prior to the registration at our center and registered between 01/01/2010 and 31/12/2011 were selected for this study. The baseline demographic pattern and the pattern of care of treatment were analyzed. SPSS version 16 (IBM Inc, Armonk, New York, U.S.) was used for analysis. Descriptive data are provided. RESULTS: A total of 761 patients were evaluable subject to the aforementioned inclusion criteria. The median age of this cohort was 75 years (70‑95 years). The most frequent primary sites of malignancies in 451 males were head neck (32.4%), lung (23.3%) and gastrointestinal (23.3%). In 310 females, the most common sites were head neck (31.6%), gynecological (18.4%) and gastrointestinal (24.5%). 228 (30%) of the patients had localized disease, 376 (49.4%) had loco‑regionally advanced disease and 145 (19.1%) had distant metastases at presentation. 334 (46.32%) of patients were treated with curative intent. On logistic regression analysis the factors that predicted use of curative intent treatment were age <75 years, performance status 0‑1, primary site and clinical extent of disease. CONCLUSION: Routine comprehensive geriatric assessment needs to be implemented in our setting as almost 50% of our geriatric patients undergo curative intent treatment.
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    Retrospective audit of clinico‑pathologic features and treatment outcomes in a cohort of elderly non‑Hodgkin’s lymphoma patients in a tertiary cancer center.
    (2015-10) Nair, C K; Patil, V M; Raghavan, V; Babu, S; Nayanar, S
    INTRODUCTION: There is limited data from India regarding elderly non‑Hodgkin’s lymphomas (NHL) patients. Hence, this audit was planned to study the clinic‑pathological features and treatment outcomes in elderly NHL patients. METHODS: Retrospective analysis of all NHL patients above age of 59 years treated at the author’s institute, between December 2010 and December 2013 was done. Case records were reviewed for baseline details, staging details, prognostic factors, treatment delivered, response, toxicity and efficacy. SPSS version 16 (IBM, Newyork) was used for analysis. Descriptive statistics was performed. Kaplan–Meir survival analysis was done for estimation of progression‑free survival (PFS) and overall survival (OS). Univariate analysis was done for identifying factors affecting PFS and OS. RESULTS: Out of 141 NHL patients, 67 patients were identified subjected to the inclusion criteria. The median age was 68 years (60–92). Majority were B‑cell NHL (86.6%). The commonest subtype in B‑cell was diffuse large B‑cell lymphoma (55.2%). Fifty‑four patients took treatment. The treatment intent was curative in 41 patients (61.2%). Among the patients receiving curative treatment, 16 patients couldn’t receive treatment in accordance with NCCN guidelines due to financial issues. Two years PFS was 55%. Two years PFS for B‑cell NHL and T‑cell NHL were 55% and 50% respectively (P = 0.982). Two years PFS for standard Rx and nonstandard Rx were 62% and 50% respectively, but it didn’t reach statistical significance (P = 0.537). Two years OS for the entire cohort was 84%. CONCLUSION: Standard treatment in accordance with guidelines can be delivered in elderly patients irrespective of age. There is a need for creating financial assistance for patients, so that potentially curative treatments are not denied.
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    Serum FSH and LH levels in fertile and subfertile men.
    (1973-09-01) Joshi, L R; Sheth, A R; Raghavan, V; Rao, S S
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    Treatment of circumscribed choroidal hemangioma using CyberKnife: A viable alternative
    (All India Ophthalmological Society, 2019-05) Agarwal, A; Raghavan, V; Rathnadevi, R; Rishi, P
    Circumscribed choroidal hemangioma is a benign vascular hamartoma without systemic associations. For symptomatic cases, treatment options are photodynamic therapy (PDT), transpupillary thermotherapy (TTT), intravitreal injection of anti-vascular endothelial growth factor (VEGF), or radiation therapy. CyberKnife radiosurgery is an image-guided radiation therapy that delivers radiation to lesions anywhere in the body with an accuracy of 0.5 mm without damage to surrounding structures. We report a case of circumscribed choroidal hemangioma which was successfully treated with CyberKnife therapy. The literature search reveals cases of uveal melanoma, intraocular, and periocular lymphoma successfully treated with CyberKnife therapy. To the best of our knowledge, this is the first report on such treatment for choroidal hemangioma.