Browsing by Author "Kesavachandran, C N"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Studies on oxidative stress induced nerve conduction deficits in cigarette smokers.
    (2011-01) Singh, Vipul Kumar; Pathak, Manoj Kumar; Bihari, Vipin; Jyoti; Patel, Devendra Kumar; Mathur, Neeraj; Kesavachandran, C N; Siddiqui, Mohd Kaleem Javed
    An important role of oxidative stress for the development of vascular and neurological complications has encouraged us to undertake a study to assess the oxidative stress induced nerve conduction deficits among cigarette smokers. Eighteen regular male cigarette smokers and twenty nine male non - smokers were diagnosed for clinical neuro-physiological tests viz., motor and sensory nerve conduction velocity (MNCV and SNCV) and redox status. Significant depletion of reduced glutathione (GSH) level (p < 0.05) and significant increase in malondialdehyde (MDA) level (p < 0.01) was found in smokers compared to non - smokers. Motor and sensory nerve conduction velocity showed no significant difference among smokers compared to non - smokers. The present study shows that smoking can induce oxidative stress among smokers but could not exacerbate to nerve conduction deficits.