Studies on oxidative stress induced nerve conduction deficits in cigarette smokers.
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Date
2011-01
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Abstract
An important role of oxidative stress for the development of vascular and neurological complications has
encouraged us to undertake a study to assess the oxidative stress induced nerve conduction deficits among
cigarette smokers. Eighteen regular male cigarette smokers and twenty nine male non - smokers were
diagnosed for clinical neuro-physiological tests viz., motor and sensory nerve conduction velocity (MNCV and
SNCV) and redox status. Significant depletion of reduced glutathione (GSH) level (p < 0.05) and significant
increase in malondialdehyde (MDA) level (p < 0.01) was found in smokers compared to non - smokers. Motor
and sensory nerve conduction velocity showed no significant difference among smokers compared to non -
smokers. The present study shows that smoking can induce oxidative stress among smokers but could not
exacerbate to nerve conduction deficits.
Description
Keywords
Cigarette smokers, Oxidative stress, Nerve conduction deficit
Citation
Singh Vipul Kumar, Pathak Manoj Kumar, Bihari Vipin, Jyoti, Patel Devendra Kumar, Mathur Neeraj, Kesavachandran C N, Siddiqui Mohd Kaleem Javed. Studies on oxidative stress induced nerve conduction deficits in cigarette smokers. Journal of Environmental Biology. 2011 Jan; 32(1): 39-42.