Browsing by Author "Kamat, J R"

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    AIDS with special reference to pediatric aspect.
    (1992-03-01) Kamat, J R; Kumta, N B
    The article discusses the disease AIDS, and its increasing incidence all over the world. The alarming rise of HIV infection amongst those tested in India is noted. The projection as made by WHO are mentioned. The various modes of transmission of HIV infection and the high risk groups for each mode are identified. Clinical manifestation of an adult case is followed by that of a pediatric patient in whom the infection is mostly transplacental. The risk of TAA amongst children is highlighted as also the difference between adult and pediatric AIDS. Diagnosis of AIDS, its management, prognosis and prevention are mentioned. The similarity between HIV-1, SIV and HIV-2 induced immunodeficiency is recorded.
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    Aortic aneurysm in a child with tuberous sclerosis.
    (2000-03-06) Bavdekar, S B; Vaideeswar, P; Bakune, R H; Sahu, D K; Kamat, J R
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    Cardiac tamponade in juvenile rheumatoid arthritis.
    (1996-05-01) Banavar, S R; Kamat, J R; Jayakar, A V
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    Chloroquine induced parkinsonism.
    (2000-01-16) Parmar, R C; Valvi, C V; Kamat, J R; Vaswani, R K
    A case of parkinsonism is reported in a 5-years-old male child following prolonged use of chloroquine. The patient presented with reduced spontaneous movements and speech with an expressionless face and a parkinsonian gait but no tremors. His investigations including CT scan brain, CSF study and serum ceruloplasmin were normal. Chloroquine was discontinued and the patient was started on oral trihexyphenidyl. The patient showed gradual recovery and the drug was successfully withdrawn. The toxic manifestations were only transient and reversible.
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    Congenital heart disease with rheumatic fever and rheumatic heart disease: a coincidence or an association?
    (2002-07-15) Bokhandi, S S; Tullu, M S; Shaharao, V B; Bavdekar, S B; Kamat, J R
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    Congenital nephrotic syndrome with clinical hypothyroidism.
    (1995-03-01) Muranjan, M N; Kher, A S; Nadkarni, U B; Kamat, J R
    A 15 month old boy with typical features of congenital nephrotic syndrome (CNS) is reported, who in addition to the renal pathology had an associated clinical hypothyroidism with low levels of total and free thyroxine and triiodothyronine and an elevated serum TSH. Improvement in the physical parameters and mental status from thyroid hormone replacement therapy is documented.
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    Cyproheptadine in severe anorexia.
    (1994-11-01) Muranjan, M N; Mordekar, S R; Bava, H S; Alavi, S; Kher, A S; Nadkarni, U B; Kamat, J R
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    Cystic tuberculosis of bones.
    (1993-05-01) Kher, A S; Bharucha, B A; Kamat, J R; Kurkure, P
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    Effect of passively transferred anti-poliovirus antibodies on seroconversion.
    (1999-01-08) Bavdekar, S B; Naik, S; Nadkarni, S S; Kamat, J R; Deshpande, J M; Vaswani, L K
    A prospective study enrolling 50 mother-infant pairs was undertaken to determine the effect of maternal antibodies on poliovirus antibody titres and seroconversion rates in infants and to determine the difference in titres and seroconversion rates following three and five doses of oral poliovaccine (OPV). Cord blood samples and samples collected 4 weeks after 3rd and 5th doses of trivalent oral poliovaccine were processed for estimation of anti-poliovirus antibody titres. These were expressed as geometric mean titres (GMT). Significance was analyzed using unpaired 't' test. The relationship between maternal antibody titres and seroconversion was determined by correlation coefficient test. Post OPV5 titres were significantly higher than post OPV3 titres for type 1 and type 2 polioviruses. Seroconversion rates against type 1, 2 and 3 polioviruses were 92.9%, 100.0% and 92.9% following OPV3 and 100.0%, 100.0% and 93.2% following OPV5. The cord blood titres did not have any relation to post-OPV3 or post-OPV5 titres. Although there is significant passive transfer of poliovirus antibodies across the placenta, this does not affect titres achieved after immunization. Post-OPV5 titres against type 1 and type 2 viruses are significantly higher than post-OPV3 titres. The seroconversion rates following OPV5 are higher than those obtained post-OPV3 but this difference is not statistically significant.
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    Experience of pediatric tetanus cases from Mumbai.
    (2000-07-25) Tullu, M S; Deshmukh, C T; Kamat, J R
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    Factor X deficiency and hemophilia A : occurrence of two different coagulation defects in a family.
    (2001-02-27) Parmar, R C; Bavdekar, S B; Sahu, D R; Kamat, J R
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    Glanzmann's thrombasthenia.
    (2001-06-14) Tullu, M S; Dixit, P S; Nair, S B; Kamat, J R; Vaswani, R K; Shetty, S D; Pawar, A R
    Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both the patients had absence of aggregation of platelets with the agonist adenosine diphosphate. Absence of the GPIIb/IIIa receptor was confirmed by flow cytometry. A short review of the disorder is presented.
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    Immunoglobulins in cerebrospinal fluid in central nervous system disorders.
    (1982-09-01) Varavi, S F; Kamat, J R; Joshi, M K; Kandoth, P W
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    Immunological response to two hepatitis B vaccines administered in two different schedules.
    (2006-06-04) Girisha, K M; Kamat, J R; Nataraj, G
    OBJECTIVES: To evaluate the antibody response to a plasma derived hepatitis B vaccine containing pre-S and S antigens and a recombinant vaccine containing only S antigen and compare the two vaccines in 0, 1, 2 and 0, 1, 6, schedules METHODS: One hundred fifty nine healthy infants were randomized to receive the vaccines in two different schedules. Anti HBs titers were estimated prior to the vaccination and then one-month following the second and third doses. RESULTS: Both the vaccines produced a high rate of seroconversion and seroprotection. The antibody response was similar with both the vaccines and the 0, 1, 6, schedule induced a significantly higher antibody level than the 0, 1, 2, schedule. CONCLUSION: 0, 1, 6 schedule produces a higher antibody level than 0, 1, 2 schedule though both the schedules have good seroconversion and seroprotection rates with both the vaccines.
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    Infantile tremor syndrome and zinc deficiency.
    (2002-02-02) Vora, R M; Tullu, M S; Bartakke, S P; Kamat, J R
    Infantile tremor syndrome is characterized by coarse tremors, mental and physical retardation, light colored brown hair, skin pigmentation and anemia. Amongst the theories proposed for the etilogy of the disorder, the nutritional theory is most accepted. In this case report, we have presented a fourteen-month-old male child with ITS and documented zinc deficiency. Though most of the previous workers have proposed vitamin-B12 deficiency as the etimology for ITS, our report suggests that zinc deficiency could also have a causative role.
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    Infantile tremor syndrome.
    (1998-04-09) Vaswani, L K; Surti, V; Bavdekar, S B; Kamat, J R
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    Intramedullary spinal cord abscess.
    (1997-05-01) Bavdekar, S B; Rao, N; Kamat, J R
    Intramedullary spinal cord abscess is a treatable cause of paraparesis. Magnetic resonance imaging is an important diagnostic modality. Combination of antimicrobial therapy and surgical intervention can provide good results in patients with subacute presentation.
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    Kawasaki disease.
    (1998-08-27) Bavdekar, S B; Vaswani, L K; Shalini, H; Chandu, K V; Gaikwad, R; Kamat, J R
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    Leptospirosis - an under-diagnosed clinical condition.
    (1999-07-29) Shah, I; Warke, S; Deshmukh, C T; Kamat, J R
    Leptospirosis is a zoonotic disease caused by leptospiral spirochaete. Two cases in children are described presenting with hepatorenal dysfunction.
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    Massive haemoptysis controlled by bronchial artery embolisation: a case report.
    (1994-01-01) Bava, H S; Kher, A; Doraiswamy, A; Malik, A K; Bharucha, B A; Kamat, J R
    Massive haemoptysis results in a high rate of mortality and morbidity. It is infrequently seen in children. Medical and surgical interventions are not very effective in controlling torrential bleeding. Therefore, newer modalities like bronchial artery embolisation are found to be promising in life threatening situations in both adults and children.