Glanzmann's thrombasthenia.
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Date
2001-06-14
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Abstract
Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both the patients had absence of aggregation of platelets with the agonist adenosine diphosphate. Absence of the GPIIb/IIIa receptor was confirmed by flow cytometry. A short review of the disorder is presented.
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20 references.
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Citation
Tullu MS, Dixit PS, Nair SB, Kamat JR, Vaswani RK, Shetty SD, Pawar AR. Glanzmann's thrombasthenia. Indian Journal of Pediatrics. 2001 Jun; 68(6): 563-6