Browsing by Author "Gupta, Sanjeev Kumar"
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Item Atorvastatin and antioxidants: The remedy for non-alcoholic fatty liver disease.(2012-03) Gupta, Sanjeev Kumar; Nikhil, S VItem Author’s Reply to 155_14 and 233_14: Functional Disability among Elderly Persons in a Rural Area of Haryana.(2014-10) Gupta, Priti; Mani, Kalaivani; Rai, Sanjay Kumar; Nongkynrih, Baridalyne; Gupta, Sanjeev KumarItem BCG immunization: is it really efficacious and cost-effective?(2006-11-09) Singh, Ritesh; Gupta, Sanjeev KumarItem Birth weight, early weight gain, and risk of type 1 diabetes.(2010-09) Agrawal, Nilesh; Gupta, Sanjeev KumarItem Childhood body mass index: a predictor of adult coronary heart disease?(2008-03-24) Singh, Ritesh; Gupta, Sanjeev KumarItem Comment on: Prevalence of depression and associated risk factors among the elderly in urban and rural field practice areas of a tertiary care institution in Ludhiana.(2015-10) Behera, Priyamadhaba; Gupta, Sanjeev KumarItem Congenital sideroblastic anemia: A report of two cases.(2009-07) Gupta, Sanjeev Kumar; Rao, Seema; Kar, Rakhee; Tyagi, Seema; Pati, Hara PrasadSideroblastic anemia, comprising of acquired and congenital forms, is a heterogeneous group of disorders characterized by the presence of ring sideroblasts in the bone marrow. Congenital sideroblastic anemia is a rare condition which is mostly X-linked, caused by mutations of delta-aminolevulinic acid synthase 2. We describe two cases of congenital sideroblastic anemia, one of them indicating an autosomal recessive inheritance, with their clinico-hematological profile. It is important to recognize this entity early in life as a significant percentage of cases respond to pyridoxine thus avoiding any long-term complications.Item Could mid-upper arm circumference be a valid proxy to the body mass index for elderly persons?(Wolters Kluwer-Medknow Publications, 2022-12) Goswami, Anil Kumar; Sathiyamoorthy, Ramadass; Mani, Kalaivani; Kant, Shashi; Gupta, Sanjeev KumarIntroduction: In elderly persons, due to physiological, anatomical, and functional changes, body mass index (BMI) may not be suitable for the assessment of nutritional status. Mid-upper arm circumference (MUAC) can be a proxy indicator to identify underweight and overweight/obesity among elderly persons. This study aimed to estimate the correlation between MUAC and BMI, and the cutoffs for MUAC using receiver operating characteristic (ROC) analysis. Material and Methods: This survey was carried out in a resettlement colony of Delhi. The participants were residents of the area who were aged 60 years or older, and selected by a simple random sampling technique. The arm span, weight, and MUAC of the participants were measured. The correlation between MUAC and BMI for gender and age group was calculated. The ROC curve was also constructed. Results: A total of 946 eligible participants were enrolled. The correlation between MUAC and BMI was 0.67 (P < 0.001) and 0.76 (P < 0.001) among men and women, respectively. The MUAC cutoff for underweight was <25 cm with a sensitivity of 68.8% and specificity of 84.9%. The area under the curve (AUC) was 0.84 (0.80–0.88). The MUAC cutoff for overweight/obesity was ?27 cm with a sensitivity of 83.9% and specificity of 64.9%, and AUC was 0.78 (0.75–0.82). Conclusion: The MUAC of the participants increased as the BMI of the participants increased. MUAC cutoff was determined using the ROC curve for underweight and overweight/obesity among elderly persons.Item Cutaneous zygomycosis: A possible postoperative complication in immunocompetent individuals.(2009-11) Tilak, Ragini; Raina, Prabhat; Gupta, Sanjeev Kumar; Tilak, Vijai; Prakash, Pradyot; Gulati, Anil KumarFungi in the class of zygomycetes usually produce serious infections in diabetics and immunocompromised hosts. Cutaneous zygomycosis is a less common form, with an unpredictable extent of anatomical involvement and clinical course. Here, we report two cases of primary cutaneous zygomycosis as postoperative complications in otherwise healthy females. Zygomycosis was suspected and specimens from the surgical debridement were examined by microbiological and histopathological studies for confirming the clinical diagnosis. Rapid diagnosis, liposomal amphotericin B, and proper debridement of affected tissue are necessary to avoid a fatal outcome.Item Does BCG vaccination protect against childhood asthma.(2010-07) Stalin, P; Gupta, Sanjeev KumarItem Does zinc supplementation prevent acute lower respiratory tract infections in children.(2011-09) Kalaiselvi, S; Gupta, Sanjeev KumarItem Domestic violence in India: Need for public health action.(2012-04) Charlette, Stephen Lena; Nongkynrih, Baridalyne; Gupta, Sanjeev KumarItem Excess Screen Time and its Associated Factors among Young Men in a Rural Community of North India(Wolters Kluwer – Medknow, 2022-09) Malhotra, Sumit; Kant, Shashi; Rath, Ramashankar; Ahamed, Farhad; Sathiyamoorthy, Ramadass; Gupta, Sanjeev KumarScreen-based media usage among young people is blooming rapidly due to technological and digital revolution. We conducted community-based cross-sectional study to determine the prevalence of excess screen time and its association with sociodemographic and behavioral patterns in a rural block of Haryana, India. Asemi-structured interview schedule was administered by trained physicians to ascertain screen time in a typical day and various socioeconomic and behavioral factors among a random sample of 860 young men aged 18–24 years. The prevalence of excess screen time was 61.8% (95% confidence interval [CI] 58.4–65.1). It was significantly associated with education (adjusted odds ratio [AOR] 1.7, 95% CI 1.1–2.6) and occupation (AOR 2.2, 95% CI 1.2–3.9) of the father and their sleep duration of ?8 h (AOR 1.6, 95% CI 1.2–2.3). Limiting the screen time as per international standards and behavioral interventions are needed for this young population.Item Functional Disability Among Elderly Persons in a Rural Area of Haryana.(2014-01) Gupta, Priti; Mani, Kalaivani; Rai, Sanjay Kumar; Nongkynrih, Baridalyne; Gupta, Sanjeev KumarBackground: The number and proportion of elderly persons is increasing, in India, as well as the world. Disability is an important indicator to measure disease burden in this group. While some chronic conditions may not be amenable to complete cure, their functional disabilities can be improved with timely and appropriate management. Objectives: The objective of the following study is to estimate the prevalence of functional disability and study its association with socio-demographic variables and self-reported chronic conditions among elderly persons in a rural area of Haryana. Materials and Methods: All persons aged 60 years and above in the randomly selected six clusters were included in this community-based cross-sectional study. Information was collected on socio-demographic variables and selfreported chronic conditions. Functional disability was defi ned as having disability in activities of daily living, or blindness or hearing impairment, or a combination of these. In multivariate analysis, backward stepwise logistic regression was carried out to study the association between the independent and dependent variables, after adjusting for confounding variables. Results: Among the 836 participants studied, the prevalence of functional disability was estimated to be 37.4% (95% confi dence interval: 34.2, 40.7). The prevalence was less among men (35.9%) than women (38.8%). The prevalence increased with age, was more common among persons who were not currently married, had diabetes and chronic obstructive pulmonary disease. Conclusion: Functional disability is common among elderly persons in the rural area. Community-based interventions are needed tto address them. Management of chronic conditions should include prevention and control of associated disability.Item Geographical information system (GIS) in decision support to control malaria--a case study of Koraput district in Orissa, India.(2009-03-31) Daash, Annjaan; Srivastava, Aruna; Nagpal, B N; Saxena, Rekha; Gupta, Sanjeev KumarItem Hemoglobin E disease with concomitant tuberculosis.(2008-10-15) Jain, Deepali; Gupta, Sanjeev Kumar; Singh, TejinderItem High body mass index and alcohol intake increase deaths due to liver disease.(2011-01) Singh, Arvind Kumar; Gupta, Sanjeev KumarItem High burden of dental caries in geriatric population of India: A systematic review.(2012-04) Srivastava, Rahul; Nongkynrih, Baridalyne; Mathur, Vijay Prakash; Goswami, Anil; Gupta, Sanjeev KumarOral health is an essential component of health throughout life. Poor oral health and untreated oral diseases can have a significant impact on the quality of life of the elderly. The objective of this study was to estimate the burden of dental caries among the elderly persons in India in the past two decades. A systematic review from available literature was carried out. Six community-based articles were included in this review. The selected studies were screened by using STROBE checklist for observational studies. All studies were found to contain the required essentials of observational studies. Weighted prevalence of dental caries experience was calculated. Trend was generated using Microsoft Excel program. The prevalence of dental caries experience ranged from 31.5 to 100%. Weighted prevalence of dental caries experience was 83.6% and 82.3% for 2000-2004 and 2005-2009, respectively. There is a high burden of dental caries in the elderly population. Treatment and restorative services need to be provided to alleviate this problem.Item Impact of initial topical medical therapy on short‑term quality of life in newly diagnosed patients with primary glaucoma.(2015-06) Arora, Vishal; Bali, Shveta Jindal; Gupta, Sanjeev Kumar; Vashisht, Praveen; Agarwal, Tushar; Sreenivas, Vishnubhatla; Dada, TanujPurpose: To evaluate the impact of initial topical medical therapy on newly diagnosed glaucoma patients using the Indian Vision Function Questionnaire (IND-VFQ33). Patients and Methods: The IND-VFQ33 was used to evaluate the quality of life (QoL) in 62 newly diagnosed patients with moderate to severe primary glaucoma and 60 healthy controls. IND-VFQ33 is a 33 item QoL assessment tool with three domains: General functioning, psychosocial impact and visual symptoms. The glaucoma patients were started on medical therapy and the QoL assessment was repeated after 3 months. Results: Glaucoma patients (mean age: 55.6 ± 9.6 years, range 40–77 years) and controls (mean age: 54.9 ± 6.7 years, 42–73 years) were matched with respect to age (P = 0.72), gender (P = 0.91) and literacy (P = 0.18). Glaucoma patients had significantly worse QoL as compared to controls at baseline across all the three domains (P < 0.001). 3 months after initiation of treatment, the overall QoL life significantly worsened from baseline with a decrease in general functioning (P < 0.001) and psychosocial impact (P = 0.041). Visual acuity in better eye significantly co-related to poor QoL at baseline (P < 0.001) and at 3 months (P = 0.04). In addition, the use of >2 topical medications significantly co-related to poor QoL at 3 months (P = 0.01). Conclusions: Evaluation using the IND-VFQ33 revealed that newly diagnosed glaucoma patients have a significant worsening of QoL after initiation of topical ocular hypotensive therapy. This should be an important consideration when educating patients about the disease and its therapy.Item Payments for healthcare: do they aggravate poverty?(2007-05-18) Singh, Ritesh; Gupta, Sanjeev Kumar