Congenital sideroblastic anemia: A report of two cases.
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Date
2009-07
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Abstract
Sideroblastic anemia, comprising of acquired and congenital forms, is a heterogeneous group of disorders characterized by the presence of ring sideroblasts in the bone marrow. Congenital sideroblastic anemia is a rare condition which is mostly X-linked, caused by mutations of delta-aminolevulinic acid synthase 2. We describe two cases of congenital sideroblastic anemia, one of them indicating an autosomal recessive inheritance, with their clinico-hematological profile. It is important to recognize this entity early in life as a significant percentage of cases respond to pyridoxine thus avoiding any long-term complications.
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Keywords
Anemia, congenital, sideroblastic anemia
Citation
Gupta Sanjeev Kumar, Rao Seema, Kar Rakhee, Tyagi Seema, Pati Hara Prasad. Congenital sideroblastic anemia: A report of two cases. Indian Journal of Pathology & Microbiology. 2009 Jul-Sept; 52(3): 424-426.