Browsing by Author "Gaikwad, S"
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Item Activity of bacterial phosphomonoesterases in batch culture.(1998-01-16) Sharma, A; Gaikwad, S; Rajput, SThe phosphomonoesterases catalyse the hydrolysis of primary esters of phosphoric acid which help the bacteria to survive in phosphate stressed environment. Ninety-five bacterial isolates were obtained from domestic sewage and industrial effluents of gelatine and soap factories at Jabalpur on a medium enriched with phosphate and were screened for phosphatase production. The phosphatase producers were tentatively identified as Escherichia coli, Vibrio vulnificus, Aeromonas hydrophila, Staphylococcus aureus, Pseudomonas maltophilia and Micrococcus varians. The in vitro studies on the production of phosphomonoesterases by bacteria was conducted. The maximum alkaline phosphatase production was recorded on 8th day of incubation by E.coli and P.maltophilia, on 10th day of incubation by V.vulnificus while M.varians and P.maltophilia produced higher acid phosphatase on 4th and 10th day of incubation respectively. The detailed investigations were done to find out the effect of various physical and chemical factors on phosphomonoesterases activity and the optimum conditions required for enzyme activity.Item Aetiological spectrum of severe community-acquired pneumonia in HIV-positive patients from Pune, India(Indian Council of Medical Research, 2018-02) Mane, A; Gujar, P; Gaikwad, S; Bembalkar, S; Gaikwad, S; Dhamgaye, T; Risbud, AItem Amyloidosis--a rare complication of psoriasis.(1994-08-01) Gaikwad, S; Hakim, A S; Paidhunghat, J V; Krishankumari, KItem Bizarre leiomyoma of uterus/smooth muscle tumor of uncertain malignant potential: A diagnostic dilemma.(2015-10) Swami, S Y; Ganjewar, R D; Gaikwad, S; Girji, D DItem A clinico-pathological study of 29 cases of gliosarcoma with special reference to two unique variants.(1997-09-05) Sarkar, C; Sharma, M C; Sudha, K; Gaikwad, S; Varma, AIn the present series, the clinical and pathological features of 29 patients of gliosarcoma diagnosed over a 12 yr period (1984-1995) are reviewed. Gliosarcomas constituted 0.48 per cent of all intracranial tumours and 4.9 per cent of all cases of glioblastoma multiforme. Most patients (68.6%) with these tumours were above 40 yr of age. However, an interesting observation in the present series was that 10.3 per cent of patients (3/29) were below 14 yr of age, the youngest being 9 months. A male preponderance was noted and the temporal lobe was involved in 55 per cent patients. Histologically, in 25 of the 29 tumours, the sarcomatous component had the appearance of fibrosarcoma. Tumours from 4 patients were unique in that one showed rhabdomyoblastic differentiation in the mesenchymal areas as confirmed by immunohistochemical stains and electron microscopy (gliomyosarcoma). In three others, the neoplastic spindle cell component was closely associated with discrete areas of osteogenic sarcoma. Follow up in 12 patients (including the 4 patients with unique variants) revealed poor outcome similar to glioblastomas. All of them died within 1 month to 1.5 yr following surgery and postoperative radiotherapy. This study possibly represents the most comprehensive and largest series of gliosarcomas being reported from India.Item Congenital orbital teratoma: a report of two cases.(1997-03-01) Sharma, M C; Sarkar, C; Gaikwad, S; Mahapatra, A K; Bahadur, SItem Correlation of ictal EEG and SPECT studies in patients of intractable epilepsy with normal MRI.(2002-12-11) Thomas, R; Bhatia, M; Bal, C S; Gaikwad, S; Singh, V P; Jain, SIdentification of the epileptic focus is the most important requirement for a successful surgical outcome in intractable epilepsy. Patients with normal MRI on high-resolution imaging pose a significant challenge in this regard. We tried to identify the epileptic focus using interictal / ictal SPECT and ictal EEG patterns in 14 patients with normal MRI. Rhythmic ictal onset activity helped to identify a single focus in 10 patients (71.43%). Inter ictal SPECT detected a focus corresponding to ictal EEG in 6 out of 10 patients (60%) in whom the test was performed. Ictal SPECT done in 5 patients correctly identified the focus in all patients (100%). Our data indicate that it is possible to obtain localization in patients with normal MRI using a combination of ictal EEG patterns and an ictal SPECT study.Item Dermatomycosis caused by common and rare fungi in Mumbai.(2008-07-18) Mathur, M; Baradkar, V P; De, A; Taklikar, S; Gaikwad, SItem Diagnostic yield in computed tomography guided stereotactic biopsies.(1998-05-29) Sharma, M C; Singh, A; Verma, A; Gaikwad, S; Sarkar, CFifty three patients underwent computerised tomography (CT) guided stereotactic biopsies from different CT defined zones of attenuation with the Leksell stereotactic apparatus from October 1993 through January 1995. Multiple lesions were seen in 16 cases and 3 of them had multiple rim enhancing lesions. Astrocytoma was the most common histological diagnosis and thalamus was the commonest site of these tumours. The overall positivity rate was 98.2%. Positive yield from the centre of the lesion, peripheral and perilesional areas was 92.1%, 54.7% and 17.6%, respectively. The definite pathological diagnosis was made in 81.1% of cases. Post-operative neurological worsening was seen in 6 patients, of which 2 recovered without any surgical treatment, in 1 patient ventriculo-peritoneal shunt was done post-biopsy whereas in another evacuation of hamatoma was done which relieved headache and vomiting while 2 patients (3.7%) died.Item Distribution of vascular lesions in ischaemic stroke: a magnetic resonance angiographic study.(1997-09-24) Padma, M V; Gaikwad, S; Jain, S; Maheshwari, M C; Misra, N KBACKGROUND: Carotid endarterectomy is now an accepted modality for reducing the threat of recurrence of ischaemic strokes in patients with severe carotid artery stenosis. However, the incidence of carotid artery stenosis, and hence the applicability of carotid endarterectomy in the Indian population is not known. We conducted a prospective study to detect and quantify extracranial and intracranial arterial lesions using magnetic resonance angiography in consecutive patients with ischaemic strokes. METHODS: All patients with recent onset of ischaemic stroke (< 4 months) had a magnetic resonance angiography done to evaluate the neck vessels as well as the circle of Willis and its branches. The degree of stenosis of the internal carotid or common carotid artery was measured according to the criteria described by the North American Symptomatic Carotid Endarterectomy Trial (NASCET) collaborators. The site and extent of the extracranial and intracranial arterial lesions were correlated with the clinical features and the pattern of infarcts on magnetic resonance imaging or computerized tomographic scan of the brain. RESULTS: The magnetic resonance angiography was abnormal in 56 out of 100 patients included in the study. Severe stenosis (> 70%) of the extracranial carotid arteries was seen in 26 patients. Lesions suitable for carotid endarterectomy were present in only 11 patients (42.3% of those with severe stenosis). CONCLUSION: Our results are in contrast to those reported from western countries where the likelihood of a surgically correctable lesion being present is 60%-70%. We found operable lesions in only 11%. Intracranial atherosclerotic disease causing strokes is probably more common in India. Therefore, although carotid endarterectomy is the only accepted surgical procedure for secondary prophylaxis of stroke, there is a need to find an alternative surgical intervention for the predominantly intracranial pathology found in the Indian population.Item Eosinophilic gastro enteritis.(1993-11-01) Gaikwad, S; Mehta, P J; Soneji, S LItem Experimental foreign body infection in mice by Staphylococcus epidermidis.(1984-10-01) Gaikwad, S; Deodhar, L PItem Factors affecting blood culture techniques in the diagnosis of paediatric septicemia.(1984-07-01) Yardi, D; Gaikwad, S; Deodhar, L PItem Fenestration of the posterior communicating artery.(2003-03-17) Tripathi, M; Goel, V; Padma, M V; Jain, S; Maheshwari, M C; Gaikwad, S; Gupta, V; Chandra, P S; Mehta, V SA 21-year-old male presented with sudden onset of right-sided third nerve paresis. Angiogram showed a fenestrated posterior communication artery on the right side and no other vascular anomalies. There was no other lesion that could suggest a cause for the third nerve weakness. Fenestration of the posterior communicating artery has not been reported till date. The case is discussed and the literature on the subject is reviewed.Item Incidence, mortality and bacteriological profile of septicemia in pediatric patients.(1984-03-01) Yardi, D; Gaikwad, S; Deodhar, LItem Isolation of Aeromonas hydrophila from a case of neonatal diarrhoea (a case report).(1986-01-01) Annapurna, E; Gaikwad, S; Kumta, N BItem Macroglossia--the presenting feature of primary amyloidosis.(1993-06-01) Gaikwad, S; Varthakavi, P; Chandalia, M; Nihalani, K DA case of amyloidosis with macroglossia as a presenting feature is described. The patient was diagnosed to have multiple myeloma at least 1 1/2 year after amyloidosis was diagnosed.Item Melanotic neuroectodermal tumour of infancy: immunohistochemical and histogenetic consideration.(1996-04-01) Sharma, M C; Mahapatra, A K; Sudha, K; Gaikwad, SItem Multifocal intracranial rhabdoid tumor.(2003-06-23) Suri, A; Singh, V P; Kale, S S; Mehta, V S; Gaikwad, SItem The myopathic variety of arthrogryposis multiplex congenita.(1995-04-01) Padma, M V; Sharma, A K; Gaikwad, S; Maheshwari, M C