Correlation of ictal EEG and SPECT studies in patients of intractable epilepsy with normal MRI.
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2002-12-11
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Abstract
Identification of the epileptic focus is the most important requirement for a successful surgical outcome in intractable epilepsy. Patients with normal MRI on high-resolution imaging pose a significant challenge in this regard. We tried to identify the epileptic focus using interictal / ictal SPECT and ictal EEG patterns in 14 patients with normal MRI. Rhythmic ictal onset activity helped to identify a single focus in 10 patients (71.43%). Inter ictal SPECT detected a focus corresponding to ictal EEG in 6 out of 10 patients (60%) in whom the test was performed. Ictal SPECT done in 5 patients correctly identified the focus in all patients (100%). Our data indicate that it is possible to obtain localization in patients with normal MRI using a combination of ictal EEG patterns and an ictal SPECT study.
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Thomas R, Bhatia M, Bal CS, Gaikwad S, Singh VP, Jain S. Correlation of ictal EEG and SPECT studies in patients of intractable epilepsy with normal MRI. Neurology India. 2002 Dec; 50(4): 440-3