Implantable cardioverter defibrillators for primary prevention in cardiomyopathies

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dc.contributor.authorKanneganti, Vineethaen_US
dc.contributor.authorBahl, Ajayen_US
dc.contributor.authorRohit, Manoj Kumaren_US
dc.contributor.authorMehrotra, Saurabhen_US
dc.date.accessioned2025-05-09T07:17:37Z
dc.date.available2025-05-09T07:17:37Z
dc.date.issued2024-04
dc.description.abstractBackground: Implantable cardioverter defibrillators (ICD) are often used as primary prevention strategy for sudden cardiac death (SCD) in young individuals. This study analyzed appropriate therapies, complications and inappropriate shocks in the real-world Indian population. Methods: All patients in the cardiomyopathy cohort under follow up who had ICD implanted as a primary pre- vention strategy were studied. The objective was to assess the incidence of appropriate ICD therapies, inap- propriate therapies and complications. ICD was interrogated and stored electrograms analyzed. Underlying arrhythmia or conditions resulting in appropriate or inappropriate ICD therapy were studied. Correlation and regression studies was done to assess for the predictors of appropriate therapy. Results: Fifty patients were followed up for a mean follow-up duration of 4.4 3.1 years with total follow up of 220.2 patient years. Appropriate ICD therapy was delivered in 16 out of 50 (32%) patients, with 65 appropriate therapies (median 2 per patient, range: 020). Inappropriate therapy delivered in 7 of the 50 (14%) patients, with 44 inappropriate therapies (median 5 per patient, range: 020). Complications occurred in 8 of the 50 (16%) patients. Overall, the rate of appropriate therapy was 29.5 per 100 patient years, that of inappropriate therapy was 19.9 per 100 patient years and the rate of complications was 3.6 per 100 patient years. Conclusions: When implanted for primary prevention in patients with cardiomyopathies over a mean period of 4.4 3.1 years, appropriate ICD therapy was delivered in 32% patients. However, inappropriate therapy (14% patients) and complications (16% patients) were also common.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Cardiology, Postgraduate Institute of Medical Education and Research, Chandigarh, Indiaen_US
dc.identifier.citationKanneganti Vineetha, Bahl Ajay, Rohit Manoj Kumar, Mehrotra Saurabh . Implantable cardioverter defibrillators for primary prevention in cardiomyopathies. Indian Heart Journal. 2024 Apr; 76(2): 118-122en_US
dc.identifier.issn0019-4832
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/242701
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber2en_US
dc.relation.volume76en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2024.03.005en_US
dc.subjectCardiomyopathyen_US
dc.subjectImplantable cardioverter defibrillatoren_US
dc.subjectSudden cardiac deathen_US
dc.titleImplantable cardioverter defibrillators for primary prevention in cardiomyopathiesen_US
dc.typeJournal Articleen_US
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