Seroepidemiology and genotypes of hepatitis C virus in Thailand.

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dc.contributor.authorSunanchaikarn, Srunthronen_US
dc.contributor.authorTheamboonlers, Apiradeeen_US
dc.contributor.authorChongsrisawat, Voranushen_US
dc.contributor.authorYoocharoen, Pornsaken_US
dc.contributor.authorTharmaphornpilas, Piyaniten_US
dc.contributor.authorWarinsathien, Porpiten_US
dc.contributor.authorSinlaparatsamee, Supakarnen_US
dc.contributor.authorPaupunwatana, Sirirajen_US
dc.contributor.authorChaiear, Kasempornen_US
dc.contributor.authorKhwanjaipanich, Sawanen_US
dc.contributor.authorPoovorawan, Yongen_US
dc.date.accessioned2009-05-27T17:15:52Z
dc.date.available2009-05-27T17:15:52Z
dc.date.issued2007-12-27en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractHCV can be classified into 6 major genotypes based on the phylogenetic analysis of the genomic sequences. The 3 major genotypes found in Thailand are 3, 1 and 6, respectively. In 2004, an epidemiological survey was carried out to evaluate the seroprevalence of HCV infections among populations aged 2-60 years in four provinces of Thailand, representing the North, Northeast, Center and South of the country, respectively. One hundred and twenty five out of 5,825 serum samples (2.15%) were positive for anti-HCV by ELISA. Fifty eight out of 100 anti-HCV positive samples (58.0%) were positive by RT-PCR of the 5'UTR. The core region of 45 representative samples was sequenced allowing classification into genotype variants 1a (6.7%), 1b (26.7%), 2a (2.2%), 2c (2.2%), 3a (51.1%), 3b (2.2%) and 6 (8.9%). This information might be crucial for public health surveillance and prevention of HCV infection.en_US
dc.description.affiliationCenter of Excellence in Viral Hepatitis Research, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationSunanchaikarn S, Theamboonlers A, Chongsrisawat V, Yoocharoen P, Tharmaphornpilas P, Warinsathien P, Sinlaparatsamee S, Paupunwatana S, Chaiear K, Khwanjaipanich S, Poovorawan Y. Seroepidemiology and genotypes of hepatitis C virus in Thailand. Asian Pacific Journal of Allergy and Immunology. 2007 Jun-Sep; 25(2-3): 175-82en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36810
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHepacivirus --geneticsen_US
dc.subject.meshHepatitis C --epidemiologyen_US
dc.subject.meshHepatitis C Antibodies --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPhylogenyen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleSeroepidemiology and genotypes of hepatitis C virus in Thailand.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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