Primary hypertrophic osteoarthropathy presenting as juvenile idiopathic arthritis: a case report
No Thumbnail Available
Date
2025-03
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Primary hypertrophic osteoarthropathy (PHO) is an inherited disorder, characterised by skin thickening of face and extremities, and periosteal proliferation of the long bones. It is caused by HPGD or SLCO2A1 gene mutations, inherited in an autosomal dominant or recessive pattern. It presents with characteristic skin changes and musculoskeletal pain. We present the case of an adolescent male patient with hypertrophic osteoarthropathy. We managed him successfully with zolendronic acid.
Description
Keywords
Pachydermoperiosteitis, Bisphosphonates, Zolendronic acid, Proliferative bone disease
Citation
Samuel M, Rajamurugan A, Subramanian R, Ramamoorthy R. Primary hypertrophic osteoarthropathy presenting as juvenile idiopathic arthritis: a case report. International Journal of Contemporary Pediatrics. 2025 Mar; 12(3): 495-497