Clinical trial to compare the analgesic efficacy of selected Traditional Medicine Formulations (TMF-06,-24,-25) on experimentally induced pain in human subjects

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dc.contributor.authorThaw Zinen_US
dc.contributor.authorMay Aye Thanen_US
dc.contributor.authorTin Tin Layen_US
dc.contributor.authorAung Naingen_US
dc.contributor.authorMaung Maung Winten_US
dc.date.accessioned2009-06-30T08:50:36Z
dc.date.available2009-06-30T08:50:36Z
dc.date.created1996-04-01en_US
dc.date.issued1996-04-01en_US
dc.description.abstractForty clinically healthy volunteers participated in the study aimed to evaluate the therapeutic efficacy of three Traditional Medicine Formulations (TMF-06, TMF-24 and TMF-25) on experimentally-induced cold compressor stimulation pain. The rationale underlying the study is that these formulations have beenproduced locally and used extensively as standard analgesics for pain relief at the Traditional Medicine Hospitals and dispensaries as well as through self-medication over-the-counter-durgs by the local community for many years but has yet received little investigative attention regarding efficacy and sefety. The study was a placebo controlled double-blind, complete cross-over single dose design using aspirin (acetyl salicylate) as positive standard and was evaluated on three basic pain response parameters namely, pain threshold, pain tolerance and pain sensitivity range. All three formulations showed a significant analgesic efficacy (p < 0.01) when compared to placebo (TMF-25 > TMF-24 > TMF-60). No, adverse effects were noted even when given at maximum recomended dose. It was concluded dose. It was concluded that the three TMFs can be used as an alternative to aspirin for the symptomatic relief of mild to moderate pain.en_US
dc.identifier.citationThaw Zin, May Aye Than, Tin Tin Lay, Aung Naing, Maung Maung Wint. Clinical trial to compare the analgesic efficacy of selected Traditional Medicine Formulations (TMF-06,-24,-25) on experimentally induced pain in human subjects. Myanmar Health Sciences Research Journal. 1996; 8(1): 41-46en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/126953
dc.subject.meshMedicine, Traditionalen_US
dc.subject.meshFormulariesen_US
dc.subject.meshAnalgesicsen_US
dc.subject.meshPain-drug therapyen_US
dc.subject.meshClinical Trialsen_US
dc.titleClinical trial to compare the analgesic efficacy of selected Traditional Medicine Formulations (TMF-06,-24,-25) on experimentally induced pain in human subjectsen_US
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