Familial combined hyperlipidemia in a North Indian kindred.

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dc.contributor.authorSriram, C Sen_US
dc.contributor.authorGulati, Sheffalien_US
dc.contributor.authorChopra, Vikasen_US
dc.contributor.authorVashist, Sumanen_US
dc.contributor.authorMenon, P S Nen_US
dc.date.accessioned2005-11-05en_US
dc.date.accessioned2009-05-30T11:23:56Z
dc.date.available2005-11-05en_US
dc.date.available2009-05-30T11:23:56Z
dc.date.issued2005-11-05en_US
dc.description.abstractFamilial combined hyperlipidemia is the most common genetic hyperlipidemia and is responsible for premature coronary artery disease. It is genetically heterogenous and no single diagnostic marker exists. The authors report an affected North Indian kindred spanning three successive generations with a possible autosomal dominant pattern of inheritance and all of them had combined dyslipidemia [elevated total cholesterol, predominantly the low density lipoprotein (LDL) fraction and elevated triglycerides]. The proband, a 4-month-old male baby, was incidentally discovered to have a lipaemic serum and so further evaluated. Both the index case and his maternal grandmother, a non-obese diabetic (type 2) with hypertension, had an atherogenic lipoprotein phenotype. Lipaemia retinalis was documented in this baby but xanthomas and coronary artery disease were not noted in the kindred. The present case report highlights the failure of dietary therapy in the proband and explores new options.en_US
dc.description.affiliationDepartment of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.en_US
dc.identifier.citationSriram CS, Gulati S, Chopra V, Vashist S, Menon PS. Familial combined hyperlipidemia in a North Indian kindred. Indian Journal of Pediatrics. 2005 Nov; 72(11): 987-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/79634
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshCholesterol --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshHyperlipidemia, Familial Combined --blooden_US
dc.subject.meshIndiaen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshTriglyceridesen_US
dc.titleFamilial combined hyperlipidemia in a North Indian kindred.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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