Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease.

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dc.contributor.authorJangid, D Ren_US
dc.contributor.authorKasliwal, R Ren_US
dc.contributor.authorBhatia, M Len_US
dc.contributor.authorTrehan, Nen_US
dc.date.accessioned1993-03-01en_US
dc.date.accessioned2009-05-30T21:49:19Z
dc.date.available1993-03-01en_US
dc.date.available2009-05-30T21:49:19Z
dc.date.issued1993-03-01en_US
dc.description.abstractAcute effects of Nifedipine, a calcium channel blocking agent (CCBA), on central haemodynamics in patients with severe hypertension and angiographically proved coronary artery disease (CAD) has been studied using Nuclear Ventriculography (MUGA). While peripheral vasodilatation leads to significant reduction of systemic blood pressure in all severe hypertensive patients (p < 0.0005 and p < 0.0001), the central haemodynamics did not improve significantly in patients without CAD (p = NS). However, in hypertensive subset of CAD, central haemodynamics significantly improves with rise of global ejection fraction (p < 0.001) and improvement of wall motion abnormalities (p < 0.001).en_US
dc.description.affiliationNuclear Cardiology Section, Escorts Heart Institute & Research Centre, New Delhi.en_US
dc.identifier.citationJangid DR, Kasliwal RR, Bhatia ML, Trehan N. Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease. Journal of the Association of Physicians of India. 1993 Mar; 41(3): 147-50en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/88969
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdministration, Sublingualen_US
dc.subject.meshAgeden_US
dc.subject.meshCardiac Output --drug effectsen_US
dc.subject.meshCoronary Disease --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGated Blood-Pool Imaging --drug effectsen_US
dc.subject.meshHemodynamics --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertension --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNifedipine --therapeutic useen_US
dc.subject.meshVentricular Function, Left --drug effectsen_US
dc.titleNuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease.en_US
dc.typeJournal Articleen_US
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