In vivo confocal microscopic characteristics of crystalline keratopathy in patients with monoclonal gammopathy: Report of two cases.

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dc.contributor.authorKocabeyoglu, Sibel
dc.contributor.authorMocan, Mehmet C
dc.contributor.authorHaznedaroglu, Ibrahim C
dc.contributor.authorUner, Aysegul
dc.contributor.authorUzunosmanoglu, Enes
dc.contributor.authorIrkec, Murat
dc.date.accessioned2015-02-03T11:10:31Z
dc.date.available2015-02-03T11:10:31Z
dc.date.issued2014-09
dc.description.abstractIn this paper, we report two cases of a 62‑year‑old patient presented with blurred vision and a 45‑year‑old male diagnosed with multiple myeloma who was referred from the Department of Oncology. Slit‑lamp examination, in vivo confocal microscopy (IVCM), systemic work‑up and serum protein electrophoresis were obtained. In both patients, slit‑lamp findings revealed bilateral diffuse subepithelial and anterior stromal crystals and IVCM showed highly reflective deposits in the corneal epithelium and stroma. The first patient was eventually diagnosed with monoclonal gammopathy of undetermined significance following bone marrow biopsy and systemic evaluation. Unusual corneal deposits may constitute the first sign of monoclonal gammopathies. IVCM may be helpful in showing the crystalline nature of the corneal deposits and guiding the clinician to the diagnosis of gammopathies. Both ophthalmologists and oncologists should be aware that corneal deposits may herald a life‑threatening hematologic disease.en_US
dc.identifier.citationKocabeyoglu Sibel, Mocan Mehmet C, Haznedaroglu Ibrahim C, Uner Aysegul, Uzunosmanoglu Enes, Irkec Murat. In vivo confocal microscopic characteristics of crystalline keratopathy in patients with monoclonal gammopathy: Report of two cases. Indian Journal of Ophthalmology. 2014 Sept ; 62 (9): 938-940.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/155752
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244741/en_US
dc.subjectCorneal depositsen_US
dc.subjectin vivo confocal microscopyen_US
dc.subjectmonoclonal gammopathy of undetermined significanceen_US
dc.subjectmultiple myelomaen_US
dc.titleIn vivo confocal microscopic characteristics of crystalline keratopathy in patients with monoclonal gammopathy: Report of two cases.en_US
dc.typeArticleen_US
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