Malaria, leprosy and dapsone.

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dc.contributor.authorSaha, Kunalen_US
dc.contributor.authorKapoor, Lataen_US
dc.contributor.authorArora, Vivek Mohanen_US
dc.contributor.authorChattopadhya, Debasishen_US
dc.date.accessioned2009-05-27T16:44:47Z
dc.date.available2009-05-27T16:44:47Z
dc.date.issued2003-09-30en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractAlthough the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous leprosy patients and 499 febrile nonleprosy control subjects. Both the surveys showed that the lepromatous patients treated with MDT had only P. vivax malaria (incidence comparable to the febrile nonleprosy controls) with complete freedom from P. falciparum. On the contrary, control sujects not taking any-leprosy drugs and staying with the leprosy patients at the same beggars' home, had both P. vivax and P. falciparum malaria. It is postulated that dapsone provided protection against P. falciparum among leprosy patients.en_US
dc.description.affiliationDelhi University, India.en_US
dc.identifier.citationSaha K, Kapoor L, Arora VM, Chattopadhya D. Malaria, leprosy and dapsone. The Southeast Asian Journal of Tropical Medicine and Public Health. 2003 Sep; 34(3): 501-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/35916
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2003_34_3/06-3050.pdfen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshDapsone --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshLeprostatic Agents --pharmacologyen_US
dc.subject.meshLeprosy --drug therapyen_US
dc.subject.meshMalaria, Falciparum --epidemiologyen_US
dc.subject.meshMalaria, Vivax --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.titleMalaria, leprosy and dapsone.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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