Lateral transfer of organophosphate degradation (opdopd) genes among soil bacteria: mode of transfer and contributions to organismal fitness

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dc.contributor.authorSiddavattam, Dayanandaen_US
dc.contributor.authorYakkala, Harshitaen_US
dc.contributor.authorSamantarrai, Devyanien_US
dc.date.accessioned2020-11-18T10:20:52Z
dc.date.available2020-11-18T10:20:52Z
dc.date.issued2019-02
dc.description.abstractGenes encoding structurally independent phosphotriesterases (PTEs) are identified in soil bacteria. These pte genes, often identified on mobilizable and self-transmissible plasmids are organized as mobile genetic elements. Their dissemination through lateral gene transfer is evident due to the detection of identical organophosphate degradation genes among soil bacteria with little orno taxonomic relationship. Convergent evolution of PTEs provided selective advantages to the bacterial strain as they convert toxic phosphotriesters (PTs) into a source of phosphate. The residues of organophosphate (OP) compounds that accumulate in a soil are proposed to contribute to the evolution of PTEs through substrate-assisted gain-of-function. This review provides comprehensiveinformation on lateral transfer of pte genes and critically examines proposed hypotheses on their evolution in the light of the short half-life of OPs in the environment. The review also proposes alternate factors that have possibly contributed to the evolution and lateral mobility of PTEs by taking into account their biology and analyses of pte genes in genomic and metagenomic databases.en_US
dc.identifier.affiliationsDepartment of Animal Sciences, School of Life Sciences, University of Hyderabad, Hyderabad 500 046, Indiaen_US
dc.identifier.citationSiddavattam Dayananda, Yakkala Harshita, Samantarrai Devyani. Lateral transfer of organophosphate degradation (opdopd) genes among soil bacteria: mode of transfer and contributions to organismal fitness. Journal of Genetics. 2019 Feb; 98: 1-10en_US
dc.identifier.issn0022-1333
dc.identifier.issn0973-7731
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215476
dc.languageenen_US
dc.publisherIndian Academy of Sciencesen_US
dc.relation.volume98en_US
dc.source.urihttps://www.ias.ac.in/article/fulltext/jgen/098/0023en_US
dc.subjectphosphotriesterasesen_US
dc.subjectopd geneen_US
dc.subjectmpd geneen_US
dc.subjectlateral gene transferen_US
dc.subjectmolecular evolution.en_US
dc.titleLateral transfer of organophosphate degradation (opdopd) genes among soil bacteria: mode of transfer and contributions to organismal fitnessen_US
dc.typeJournal Articleen_US
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