Varidans streptococci in the oral flora of the patients at risk for infective endocarditis: species and penicillin susceptibilities.

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dc.contributor.authorChayakul, Pantipen_US
dc.contributor.authorHortiwakul, Ratrien_US
dc.contributor.authorYipintsoi, Tadaen_US
dc.contributor.authorIngviya, Natnichaen_US
dc.date.accessioned2009-05-27T21:50:29Z
dc.date.available2009-05-27T21:50:29Z
dc.date.issued2002-07-26en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractThis study examined viridans streptococci (SV) in oral flora of patients at risk of infective endocarditis (IE) by obtaining 57 isolates from gum-tooth margin swabs of 3 groups of patients. Penicillin minimal inhibitory concentrations (MICs) were determined by E test. Group 1 was from 30 patients with prosthetic heart valves who did not receive antimicrobial agents within 3 months prior to recruitment. Group 2 consisted of 21 patients with known rheumatic heart diseases who regularly received penicillin prophylaxis. Group 3 was 2 patients with IE caused by SV in whom dental swabs were performed before and on the third day of treatment. Streptococcus mitis was found most frequently (49% among 51 oral isolates of SV from patients in group 1 and 2) and in both blood cultures of IE patients. Ninety-four per cent of the isolates were penicillin-susceptible and the rest were intermediate-resistant (IR) equally distributed in both groups 1 and 2. In 2 patients with IE, oral SV obtained after 3 days of penicillin therapy had MICs rising 3 and 5 folds of the baselines. It is suggested that surveillance of susceptibilities of oral SV in patients at risk for IE should be kept up since this will affect the dose and type of antimicrobial agents in IE prophylaxis.en_US
dc.description.affiliationDepartment of Medicine, Faculty of Medicine, Prince of Songkla University, Thailand.en_US
dc.identifier.citationChayakul P, Hortiwakul R, Yipintsoi T, Ingviya N. Varidans streptococci in the oral flora of the patients at risk for infective endocarditis: species and penicillin susceptibilities. Journal of the Medical Association of Thailand. 2002 Jul; 85(7): 825-30en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/45496
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshEndocarditis, Bacterial --etiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMouth Mucosa --microbiologyen_US
dc.subject.meshPenicillin Resistanceen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshStreptococcus oralis --drug effectsen_US
dc.titleVaridans streptococci in the oral flora of the patients at risk for infective endocarditis: species and penicillin susceptibilities.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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