A Study of Thyroid Profile Status and its Correlation with Lipid Profile in a Tertiary Care Centre

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Date
2024-07
Journal Title
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Publisher
International Society for Contemporary Medical Research
Abstract
Introduction: The thyroid hormone, which has varying effects on cell metabolism in various organs, is a crucial component of healthy homeostasis. It was discovered that thyroid hormones, which are classified as catabolic hormones, control several metabolic processes, such as lipid synthesis, mobilization, and breakdown. Aim: To study thyroid profile status and its correlation with lipid profile in a tertiary care centre Material and methods: It is a Cross-sectional study. All the above samples were taken from the outpatient department (OPD). 5 ml of venous blood was collected in yellow topped vacutainer. Analysis of all the analytes Total Cholesterol, Triglycerides and HDL Cholesterol was made using a fully automated Biochemistry analyzer (Siemens Dimension EXL 200) LDL Cholesterol was calculated based on the Friedewald formula. Serum T3, T4, and TSH were analyzed using VIDAS. Two sets were tabulated, in one set when TSH value was less than 5uIU/mL, and in the second set the value of TSH was more than 5uIU/mL. Correlation of TSH value at both the set were done. Results: Spearman test is used. Compare the TSH value at both levels, 0-5 and 5.1-10.5uIU/mL, to serum total cholesterol and serum triglyceride, we found that there was no significant correlation between the two. Conclusion: It is not necessary that alteration in the thyroid hormones will affect the levels of serum total cholesterol and serum triglyceride in the body.
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Keywords
Thyroid Profile, Lipid Profile
Citation
Ashwani, Kumar Ashwini, Gupta Anurodh, MK Sibin . A Study of Thyroid Profile Status and its Correlation with Lipid Profile in a Tertiary Care Centre. International Journal of Contemporary Medical Research. 2024 Jul; 11(7): 1-4