Increased prevalence of extended spectrum beta lactamase producers in neonatal septicaemic cases at a tertiary referral hospital.

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dc.contributor.authorBhattacharjee, Aen_US
dc.contributor.authorSen, M Ren_US
dc.contributor.authorPrakash, Pen_US
dc.contributor.authorGaur, Aen_US
dc.contributor.authorAnupurba, Sen_US
dc.date.accessioned2008-10-01en_US
dc.date.accessioned2009-05-28T09:22:49Z
dc.date.available2008-10-01en_US
dc.date.available2009-05-28T09:22:49Z
dc.date.issued2008-10-01en_US
dc.description.abstractEmergence of extended spectrum beta lactamases (ESBLs) producing strains of gram negative bacteria, as one of the leading cause of septicaemia often complicates the clinical and therapeutic outcome. The present study was undertaken to investigate the prevalence of ESBLs in bacteria isolated from neonatal septicaemic cases along with their antimicrobial sensitivity pattern. Blood samples were collected from 243 suspected cases of neonatal septicaemia. Apart from susceptibility testing, all the gram negative isolates were subjected to phenotypic tests for ESBL production. Amongst the positive test samples (n = 115), 84 were gram negative rods. ESBL was detected in 26 (32%) isolates. Results indicate that routine ESBL detection should be made imperative and empirical use of third generation cephalosporins must be discouraged.en_US
dc.description.affiliationDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India. mr_senbhu@yahoo.comen_US
dc.identifier.citationBhattacharjee A, Sen MR, Prakash P, Gaur A, Anupurba S. Increased prevalence of extended spectrum beta lactamase producers in neonatal septicaemic cases at a tertiary referral hospital. Indian Journal of Medical Microbiology. 2008 Oct-Dec; 26(4): 356-60en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53839
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshBacteremia --epidemiologyen_US
dc.subject.meshCephalosporins --pharmacologyen_US
dc.subject.meshDrug Resistance, Bacterialen_US
dc.subject.meshGram-Negative Bacteria --drug effectsen_US
dc.subject.meshGram-Negative Bacterial Infections --epidemiologyen_US
dc.subject.meshHospitals, University --statistics & numerical dataen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshIntensive Care Units, Neonatalen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshbeta-Lactamases --biosynthesisen_US
dc.titleIncreased prevalence of extended spectrum beta lactamase producers in neonatal septicaemic cases at a tertiary referral hospital.en_US
dc.typeJournal Articleen_US
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