Extended spectrum beta lactamase producing Klebsiella pneumoniae in neonatal intensive care unit.

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dc.contributor.authorKrishna, B V Sen_US
dc.contributor.authorPatil, Asha Ben_US
dc.contributor.authorChandrasekhar, M Ren_US
dc.date.accessioned2007-07-19en_US
dc.date.accessioned2009-05-30T13:33:45Z
dc.date.available2007-07-19en_US
dc.date.available2009-05-30T13:33:45Z
dc.date.issued2007-07-19en_US
dc.description.abstractOBJECTIVE: As infections due to Extended Spectrun beta Lactamase (ESbetaL) producing Klebsiella pneumoniae were increasing in the NICU at Karnataka Institute of Medical Sciences Hospital, Hubli, India, the present study was carried out to identify any environmental sources and the mode of transmission. METHODS: Environmental samples from various sites were collected monthly for a period of six months. RESULTS: ESbetaL producing K. pneumoniae were isolated from all the sites except room air at least on one occasion. ESbetaL producing K. pneumoniae was always isolated from one of the incubators, medicine trolley and sink; while at least one of the health care workers carried it in the hands four out of six times tested. ESbeta L producing K. pneumoniae with similar antibiogram were also isolated from the clinical samples obtained from the neonates. CONCLUSION: Widespread use of third generation cephalosporins as a pre-emptive antibiotic for suspected cases of septicaemia may have contributed to emergence of ESbetaL producing K. pneumoniae in addition to other risk factors. ESbetaL producing K. pneumoniae have extensively colonised the environment of the NICU. Transmission of these pathogens to the neonates has probably occurred through the healthcare workers. Efforts to improve hand hygiene among the healthcare workers and mothers are urgently needed.en_US
dc.description.affiliationDepartment of Microbiology, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, United Kingdom. bvsk@yahoo.comen_US
dc.identifier.citationKrishna BV, Patil AB, Chandrasekhar MR. Extended spectrum beta lactamase producing Klebsiella pneumoniae in neonatal intensive care unit. Indian Journal of Pediatrics. 2007 Jul; 74(7): 627-30en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/81810
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshCross Infection --microbiologyen_US
dc.subject.meshDrug Resistance, Multiple, Bacterialen_US
dc.subject.meshEquipment Contaminationen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshIntensive Care Units, Neonatalen_US
dc.subject.meshKlebsiella Infections --microbiologyen_US
dc.subject.meshKlebsiella pneumoniae --isolation & purificationen_US
dc.subject.meshbeta-Lactamases --metabolismen_US
dc.titleExtended spectrum beta lactamase producing Klebsiella pneumoniae in neonatal intensive care unit.en_US
dc.typeJournal Articleen_US
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