Body fluids: Comparison of liquid based cytology with conventional cytopreparatory technique

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dc.contributor.authorNemade, SHen_US
dc.contributor.authorKamal, MM.en_US
dc.date.accessioned2023-08-10T07:33:14Z
dc.date.available2023-08-10T07:33:14Z
dc.date.issued2023-03
dc.description.abstractIntroduction: In the diagnosis of malignant tumors, cytological examinations of various body fluids are useful. For the preparation of body fluid, many methods are used till date. The use of liquid-based cytology is new upcoming in the field. Aim: To examine the performance of liquid-based cytology on body cavity fluids as compared to conventional cytopreparatory techniques. Methodology: In the present study, 700 body fluid samples were processed by both liquid- based cytology (BD SurePath™) and conventional cytopreparatory technique (Thick & Thin). The performance of both techniques was compared in terms of “smear quality” and “overall diagnostic test performance.” Results: Out of 155 body fluid samples from proven malignancy patients, 32 (20.65%) were reported as Positive for malignancy, 23 (14.84%) as Suspicious of malignancy, and 100 (64.51%) as Negative for malignancy by CS (Thick and Thin). A total of 44 (28.39%) were reported as Positive for malignancy, 12 (7.74%) as Suspicious of malignancy, and 99 (63.87%) as Negative for malignancy by LBC. Conclusion: Liquid-based cytology is advantageous over conventional techniques in cytomorphology of body fluids, but not better in sensitivity and specificity. Also saves cytopathologist's valuable time for screening.en_US
dc.identifier.affiliationsDepartment of Pathology, Government Medical College, Nagpur; Dr. Nemade Nidan Pathology Laboratory and Research Center, Akot, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Government Medical College, Nagpur, Maharashtra, Indiaen_US
dc.identifier.citationNemade SH, Kamal MM.. Body fluids: Comparison of liquid based cytology with conventional cytopreparatory technique. Indian Journal of Pathology & Microbiology. 2023 Mar; 66(1): 75-80en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/223389
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume66en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_1182_21en_US
dc.subjectCytomorphology, cytopathology, liquid-based cytologyen_US
dc.titleBody fluids: Comparison of liquid based cytology with conventional cytopreparatory techniqueen_US
dc.typeJournal Articleen_US
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