Occurrence of extended spectrum beta-lactamases among Enterobacteriaceae spp. isolated at a tertiary care institute.

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dc.contributor.authorKumar, M Sen_US
dc.contributor.authorLakshmi, Ven_US
dc.contributor.authorRajagopalan, Ren_US
dc.date.accessioned2006-07-17en_US
dc.date.accessioned2009-05-28T09:21:31Z
dc.date.available2006-07-17en_US
dc.date.available2009-05-28T09:21:31Z
dc.date.issued2006-07-17en_US
dc.description.abstractIncreasing resistance to third generation cephalosporins has become a cause for concern especially among Enterobacteriaceae that cause nosocomial infections. The prevalence of extended spectrum beta-lactamases (ESBLs) among members of Enterobacteriaceae constitutes a serious threat to current beta-lactam therapy leading to treatment failure and consequent escalation of costs. A detailed study was initiated to identify the occurrence of ESBLs among the Enterobacteriaceae isolates at a tertiary care hospital using the double disk potentiation technique. Antibiogram profiles were determined to commonly used antibiotics and confirmation of ESBLs production was carried out by the disk diffusion assay using ceftazidime and cefotaxime in the presence and absence of clavulanic acid. Our results indicate that the majority of ESBLs were expressed in Escherichia coli.en_US
dc.description.affiliationDiscovery Research, Dr. Reddy's Laboratories Ltd., Hyderabad - 500 049, India. sitaramkumarm@gmail.comen_US
dc.identifier.citationKumar MS, Lakshmi V, Rajagopalan R. Occurrence of extended spectrum beta-lactamases among Enterobacteriaceae spp. isolated at a tertiary care institute. Indian Journal of Medical Microbiology. 2006 Jul; 24(3): 208-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/53807
dc.language.isoengen_US
dc.source.urihttps://www.ijmm.orgen_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshCefotaxime --pharmacologyen_US
dc.subject.meshEnterobacteriaceae --drug effectsen_US
dc.subject.meshEnterobacteriaceae Infections --microbiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshbeta-Lactam Resistanceen_US
dc.subject.meshbeta-Lactamases --metabolismen_US
dc.titleOccurrence of extended spectrum beta-lactamases among Enterobacteriaceae spp. isolated at a tertiary care institute.en_US
dc.typeJournal Articleen_US
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