Coinfections among patients with COVID-19: A retrospective analysis

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Date
2025-01
Journal Title
Journal ISSN
Volume Title
Publisher
Eldaghayes Publisher
Abstract
Background: From 2019 to 2021, the world was caught in the grappling clutches of the novel coronavirus, claiming almost 6.9 million lives, thus adding to the burden on the healthcare system. Aim: To determine the rate of coinfection in COVID-19-affected individuals, describe their characteristics, and compare mortality rates. Methods: Patients admitted with COVID-19 pneumonia between June 2020 and March 2021 who tested positive were identified from the hospital’s real-time reverse transcriptase-polymerase chain reaction records, and their data were collected using the hospital information system. The primary outcome of this study was the identification of all-cause in-hospital mortality. Proportions were compared using the Fisher exact test, and continuous variables were compared using the student t-test. Results: The most common coinfection was bacterial pneumonia (36.7%). Although mortality was observed, it was not statistically significant. The mean length of stay in patients with coinfection (11 days) was longer than that in patients without coinfection. On univariate analysis, a significantly higher C Reactive Protein (CRP) level was observed in patients with coinfection than in patients without coinfection. Conclusion: This study sheds light on the complex interplay between coinfections and their outcomes, adding to the research needed to optimize patient care during a similar future pandemic.
Description
Keywords
COVID-19, Pneumonia, Coinfection.
Citation
Pinnam HS, Shankaregowda R, Sumana M, Tejashree A, Mahale RP, Sowmya G, Rao MR, Chitharagi VB, Deepashree R, Sujatha S, Murthy NS, Kumthekar I, Agrawal A.. Coinfections among patients with COVID-19: A retrospective analysis . International Journal of Medical Science and Public Health. 2025 Jan; 11(1): 8-14