External clues to inner malformations.

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dc.contributor.authorGupta, Den_US
dc.contributor.authorVaiphei, Ken_US
dc.contributor.authorBanerjee, C Ken_US
dc.contributor.authorJoshi, Ken_US
dc.contributor.authorVashishta, R Ken_US
dc.contributor.authorRadotra, B Den_US
dc.contributor.authorDas, Aen_US
dc.contributor.authorBanerjee, A Ken_US
dc.date.accessioned1998-10-29en_US
dc.date.accessioned2009-05-29T10:55:58Z
dc.date.available1998-10-29en_US
dc.date.available2009-05-29T10:55:58Z
dc.date.issued1998-10-29en_US
dc.description.abstractA malformation is a morphological defect of an organ, or a larger region of the body resulting from an intrinsically abnormal developmental process. In this analysis of 1421 neonatal autopsies performed between 1984 and 1993, 243 (17.1%) cases showed malformations. The data was analysed to find external cues to internal malformations. Twenty three (85%) of the 27 neonates with various facial abnormalities had associated internal malformations in the form of cardiac (n = 11; 40%), renal (n = 7; 25%), or gastrointestinal (n = 3; 11%) abnormalities and diaphragmatic hernia (n = 2). Sixty seven neonates had neural abnormalities. These were associated with cardiac (n = 7; 10%), renal (n = 12; 18%) or gastrointestinal (n = 7; 10%) abnormalities; 43 cases, however, did not have any associated malformations. Renal malformations (n = 66) had highest association with skeletal abnormalities (n = 9; 22%). As many as 45(76%) of the 59 cases with cardiac abnormalities had no external anomalies. Five cases of hypoplastic lungs were seen, all associated with external malformations.en_US
dc.description.affiliationDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.en_US
dc.identifier.citationGupta D, Vaiphei K, Banerjee CK, Joshi K, Vashishta RK, Radotra BD, Das A, Banerjee AK. External clues to inner malformations. Indian Journal of Pathology & Microbiology. 1998 Oct; 41(4): 443-52en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/72968
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAbnormalities, Multiple --pathologyen_US
dc.subject.meshAutopsyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshMaleen_US
dc.subject.meshRetrospective Studiesen_US
dc.titleExternal clues to inner malformations.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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