Diabetes control, dyslipidemia, hsCRP and mild cognitive impairment in non-elderly people with type 2 diabetes mellitus

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dc.contributor.authorKumar, Naveenen_US
dc.contributor.authorSingh, Veer Bahaduren_US
dc.contributor.authorMeena, Babu Lalen_US
dc.contributor.authorKumar, Deepaken_US
dc.contributor.authorKumar, Harishen_US
dc.contributor.authorTiwari, Arunen_US
dc.date.accessioned2020-11-18T09:57:34Z
dc.date.available2020-11-18T09:57:34Z
dc.date.issued2019-02
dc.description.abstractBackground: Mild Cognitive Impairment (MCI) a transitional stage between normal aging and dementia has been observed more in people with diabetes when compared with general population. The risk factors for MCI in type 2 diabetes mellitus (T2DM) have been defined in elderly patients and aging may itself contribute to declining in cognitive functions. As the large number people with T2DM are under 60years, the prevalence of MCI and factors contributing to it are not much studied. So, this study aimed to find out the factors contributing to MCI in non-elderly T2DM patients.Methods: In this cross-sectional study, 257 patients with T2DM underwent cognitive assessment by Montreal cognitive assessment test and the cognitive levels were correlated with their glycosylated hemoglobin, lipid profile, and highly sensitive C-reactive protein (hsCRP).Results: The prevalence of mild cognitive impairment (MCI) was 64.2%.  MCI significantly correlated with duration of diabetes, socioeconomic status, HbA1c, serum triglycerides, low-density lipoprotein, very low-density lipoprotein and hsCRP levels. The factors that were statistically insignificant were body mass index and high-density lipoprotein levels.Conclusions: Cognitive impairment is seen even in non-elderly T2DM patients. It should be considered along with the other complications of diabetes and individuals with T2DM should be screened for cognitive impairment to prevent progression to dementia.en_US
dc.identifier.affiliationsDepartment of General Medicine, Sardar Patel Medical College, Bikaner, Rajasthan, Indiaen_US
dc.identifier.citationKumar Naveen, Singh Veer Bahadur, Meena Babu Lal, Kumar Deepak, Kumar Harish, Tiwari Arun. Diabetes control, dyslipidemia, hsCRP and mild cognitive impairment in non-elderly people with type 2 diabetes mellitus. International Journal of Research in Medical Sciences. 2019 Feb; 7(2): 372-377en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211130
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20190337en_US
dc.subjectDyslipidemiaen_US
dc.subjectHbA1cen_US
dc.subjectHigh sensitivity C-reactive proteinen_US
dc.subjectMild cognitive impairmenten_US
dc.subjectMontreal cognitive assessmenten_US
dc.subjectType 2 diabetes mellitusen_US
dc.titleDiabetes control, dyslipidemia, hsCRP and mild cognitive impairment in non-elderly people with type 2 diabetes mellitusen_US
dc.typeJournal Articleen_US
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